caa a22 4500 475831314 CHVBK 20180406123840.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1007/s100960000353 doi (NATIONALLICENCE)springer-10.1007/s100960000353 Surveillance of Penicillin-Resistant Streptococcus pneumoniae in One American Metropolitan Area, 1989-1998 [Elektronische Daten] [R. T. Sahloul, R. J. Stanek, M. A. Mufson]  The emergence of invasive penicillin-resistant (PRSP) and multidrug-resistant (MDRP) Streptococcus pneumoniae was tracked from 1989 to 1998 in one medium-sized metropolitan area in the USA, encompassing western West Virginia, including Huntington, the only major city, and neighboring sections of Kentucky and Ohio. Capsular serotyping and antibiotic sensitivity tests were performed on 350 community-acquired isolates comprising 93.1% of all pneumococcal isolates identified. The incidence of PRSP increased from 3 to 10% during the 10 years of the study. Twenty-nine (22.1%) of 131 isolates of serotypes 6, 9, 14, 19, and 23 were PRSP (one-fourth were MDRP) and 1 (0.5%) of 219 other serotypes was PRSP (serotype 35). Invasive PRSP occurred most frequently in young children and in adults aged 80 years and older, 8.9 and 10.9 cases per 100,000 persons, respectively. Springer-Verlag Berlin Heidelberg, 2000 Sahloul R. T. Department of Medicine, Marshall University School of Medicine, 1600 Medical Center Drive, Suite G500, Huntington, WV 25701-3655, USA e-mail: mufson@marshall.edu, US aut Stanek R. J. Department of Medicine, Marshall University School of Medicine, 1600 Medical Center Drive, Suite G500, Huntington, WV 25701-3655, USA e-mail: mufson@marshall.edu, US aut Mufson M. A. Department of Medicine, Marshall University School of Medicine, 1600 Medical Center Drive, Suite G500, Huntington, WV 25701-3655, USA e-mail: mufson@marshall.edu, US aut https://doi.org/10.1007/s100960000353 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s100960000353 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sahloul R. T. Department of Medicine, Marshall University School of Medicine, 1600 Medical Center Drive, Suite G500, Huntington, WV 25701-3655, USA e-mail: mufson@marshall.edu, US aut NATIONALLICENCE 700 1- Stanek R. J. Department of Medicine, Marshall University School of Medicine, 1600 Medical Center Drive, Suite G500, Huntington, WV 25701-3655, USA e-mail: mufson@marshall.edu, US aut NATIONALLICENCE 700 1- Mufson M. A. Department of Medicine, Marshall University School of Medicine, 1600 Medical Center Drive, Suite G500, Huntington, WV 25701-3655, USA e-mail: mufson@marshall.edu, US aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer