caa a22 4500 475831330 CHVBK 20180406123840.0 cr unu---uuuuu 170329e20001001xx s 000 0 eng 10.1007/s100960000352 doi (NATIONALLICENCE)springer-10.1007/s100960000352 High Prevalence of GB Virus C/Hepatitis G Virus RNA and Antibodies in Patients Infected with Human Immunodeficiency Virus Type 1 [Elektronische Daten] [D. Rey, J. Vidinic-Moularde, P. Meyer, C. Schmitt, S. Fritsch, J. M. Lang, F. Stoll-Keller]  The prevalence of GB virus C (GBV-C)/ hepatitis G virus (HGV) RNA and antibodies to the structural E2 protein was investigated in a cohort of HIV-1 infected patients. Of 346 individuals, RNA was detected in 143 and E2 antibodies were detected in 73, for an overall prevalence of 62.4%. Intravenous drug use and homosexuality were identified as major transmission risk factors. GBV-C/HGV RNA prevalence was associated with hepatitis B coinfection, whereas antibodies to E2 were associated with older age and lower CD4+ cell counts. GBV-C/HGV infection was frequent in this group of HIV-infected patients and was associated with older age, lower CD4+ cell counts, and the presence of hepatitis B surface antigen. Springer-Verlag Berlin Heidelberg, 2000 Rey D. CISIH, Clinique Médicale A, Hôpitaux Universitaires, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France e-mail: david.rey@chru-strasbourg.fr, FR aut Vidinic-Moularde J. Institut de Virologie, Faculté de Médecine, 3 rue Koeberlé, 67000 Strasbourg, France, FR aut Meyer P. Département d'Information Médicale, Hôpitaux Universitaires, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France, FR aut Schmitt C. Institut de Virologie, Faculté de Médecine, 3 rue Koeberlé, 67000 Strasbourg, France, FR aut Fritsch S. Institut de Virologie, Faculté de Médecine, 3 rue Koeberlé, 67000 Strasbourg, France, FR aut Lang J. M. CISIH, Clinique Médicale A, Hôpitaux Universitaires, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France e-mail: david.rey@chru-strasbourg.fr, FR aut Stoll-Keller F. Institut de Virologie, Faculté de Médecine, 3 rue Koeberlé, 67000 Strasbourg, France, FR aut https://doi.org/10.1007/s100960000352 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s100960000352 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rey D. CISIH, Clinique Médicale A, Hôpitaux Universitaires, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France e-mail: david.rey@chru-strasbourg.fr, FR aut NATIONALLICENCE 700 1- Vidinic-Moularde J. Institut de Virologie, Faculté de Médecine, 3 rue Koeberlé, 67000 Strasbourg, France, FR aut NATIONALLICENCE 700 1- Meyer P. Département d'Information Médicale, Hôpitaux Universitaires, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France, FR aut NATIONALLICENCE 700 1- Schmitt C. Institut de Virologie, Faculté de Médecine, 3 rue Koeberlé, 67000 Strasbourg, France, FR aut NATIONALLICENCE 700 1- Fritsch S. Institut de Virologie, Faculté de Médecine, 3 rue Koeberlé, 67000 Strasbourg, France, FR aut NATIONALLICENCE 700 1- Lang J. M. CISIH, Clinique Médicale A, Hôpitaux Universitaires, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France e-mail: david.rey@chru-strasbourg.fr, FR aut NATIONALLICENCE 700 1- Stoll-Keller F. Institut de Virologie, Faculté de Médecine, 3 rue Koeberlé, 67000 Strasbourg, France, FR aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer