caa a22 4500 475831470 CHVBK 20180406123841.0 cr unu---uuuuu 170329e20000801xx s 000 0 eng 10.1007/s100960000288 doi (NATIONALLICENCE)springer-10.1007/s100960000288 Secondary Resistance Among 554 Isolates of Helicobacter pylori After Failure of Therapy [Elektronische Daten] [M. Heep, M. Kist, S. Strobel, D. Beck, N. Lehn]  In a study to determine secondary resistance among Helicobacter pylori isolates, gastroenterologists from several German cities submitted over a 3-year period to centre A (Regensburg) or centre B (Freiburg) gastric biopsies from patients in whom one or more therapies to eradicate Helicobacter pylori had failed. Rates of resistance among the collections of 302 (centre A) and 252 (centre B) isolates were, respectively, as follows: to metronidazole, 75% and 66%; to clarithromycin, 58% and 49%; to amoxicillin, 0%; to ciprofloxacin, 9%; to doxycycline, 0%; and to rifampin, 0%. Resistance to clarithromycin was associated with metronidazole resistance in 89% and 85% of the isolates in centre A and centre B, respectively. Springer-Verlag Berlin Heidelberg, 2000 Heep M. Institute for Medical Microbiology and Hygiene, University of Freiburg, Hermann-Herder-Strasse 11, 79104 Freiburg, Germany e-mail: Markus-Heep@web.de, DE aut Kist M. Institute for Medical Microbiology and Hygiene, University of Freiburg, Hermann-Herder-Strasse 11, 79104 Freiburg, Germany e-mail: Markus-Heep@web.de, DE aut Strobel S. Institute for Medical Microbiology and Hygiene, University of Freiburg, Hermann-Herder-Strasse 11, 79104 Freiburg, Germany e-mail: Markus-Heep@web.de, DE aut Beck D. Institut für Medizinische Mikrobiologie, Uniklinik Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany, DE aut Lehn N. Institut für Medizinische Mikrobiologie, Uniklinik Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany, DE aut https://doi.org/10.1007/s100960000288 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s100960000288 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Heep M. Institute for Medical Microbiology and Hygiene, University of Freiburg, Hermann-Herder-Strasse 11, 79104 Freiburg, Germany e-mail: Markus-Heep@web.de, DE aut NATIONALLICENCE 700 1- Kist M. Institute for Medical Microbiology and Hygiene, University of Freiburg, Hermann-Herder-Strasse 11, 79104 Freiburg, Germany e-mail: Markus-Heep@web.de, DE aut NATIONALLICENCE 700 1- Strobel S. Institute for Medical Microbiology and Hygiene, University of Freiburg, Hermann-Herder-Strasse 11, 79104 Freiburg, Germany e-mail: Markus-Heep@web.de, DE aut NATIONALLICENCE 700 1- Beck D. Institut für Medizinische Mikrobiologie, Uniklinik Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany, DE aut NATIONALLICENCE 700 1- Lehn N. Institut für Medizinische Mikrobiologie, Uniklinik Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer