caa a22 4500 475831616 CHVBK 20180406123841.0 cr unu---uuuuu 170329e20000801xx s 000 0 eng 10.1007/s100960000318 doi (NATIONALLICENCE)springer-10.1007/s100960000318 Influence of Rheumatoid Factor on the Specificity of a Rapid Immunochromatographic Test for Diagnosing Dengue Infection [Elektronische Daten] [T. Jelinek, J. Wastlhuber, S. Pröll, M. Schattenkirchner, T. Löscher] In order to determine the influence of rheumatoid factor in serum specimens on the specificity of an immunochromatographic test for the detection of antibodies against dengue virus, 50 clinical specimens containing rheumatoid factor were evaluated for cross reactivity with a commercially available assay. While specificity for the detection of immunoglobulin (Ig) G antibodies was 100%, the IgM component of the test showed false-positive results in 26% of cases. Thus, it is important to consider interference by rheumatoid factor when using immunochromatographic assays for the detection of specific IgM produced during dengue infection. Springer-Verlag Berlin Heidelberg, 2000 Jelinek T. Department of Infectious Diseases and Tropical Medicine, University of Munich, Leopoldstrasse 5, 80802 Munich, Germany e-mail: jelinek@lrz.uni-muenchen.de, DE aut Wastlhuber J. Rheuma-Einheit der Universität München, Medizinische Poliklinik des Klinikums Innenstadt, Ludwig-Maximilians-University, Munich, Germany, DE aut Pröll S. Department of Infectious Diseases and Tropical Medicine, University of Munich, Leopoldstrasse 5, 80802 Munich, Germany e-mail: jelinek@lrz.uni-muenchen.de, DE aut Schattenkirchner M. Rheuma-Einheit der Universität München, Medizinische Poliklinik des Klinikums Innenstadt, Ludwig-Maximilians-University, Munich, Germany, DE aut Löscher T. Department of Infectious Diseases and Tropical Medicine, University of Munich, Leopoldstrasse 5, 80802 Munich, Germany e-mail: jelinek@lrz.uni-muenchen.de, DE aut https://doi.org/10.1007/s100960000318 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s100960000318 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jelinek T. Department of Infectious Diseases and Tropical Medicine, University of Munich, Leopoldstrasse 5, 80802 Munich, Germany e-mail: jelinek@lrz.uni-muenchen.de, DE aut NATIONALLICENCE 700 1- Wastlhuber J. Rheuma-Einheit der Universität München, Medizinische Poliklinik des Klinikums Innenstadt, Ludwig-Maximilians-University, Munich, Germany, DE aut NATIONALLICENCE 700 1- Pröll S. Department of Infectious Diseases and Tropical Medicine, University of Munich, Leopoldstrasse 5, 80802 Munich, Germany e-mail: jelinek@lrz.uni-muenchen.de, DE aut NATIONALLICENCE 700 1- Schattenkirchner M. Rheuma-Einheit der Universität München, Medizinische Poliklinik des Klinikums Innenstadt, Ludwig-Maximilians-University, Munich, Germany, DE aut NATIONALLICENCE 700 1- Löscher T. Department of Infectious Diseases and Tropical Medicine, University of Munich, Leopoldstrasse 5, 80802 Munich, Germany e-mail: jelinek@lrz.uni-muenchen.de, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer