caa a22 4500 475831977 CHVBK 20180406123842.0 cr unu---uuuuu 170329e20000401xx s 000 0 eng 10.1007/s100960050466 doi (NATIONALLICENCE)springer-10.1007/s100960050466 LaRocco M. T. Department of Pathology, St. Luke's Episcopal Hospital, PO Box 20269, M.C. 4-265, Houston, TX 77225-0269, USA e-mail: mlarocco@sleh.com, US aut Evaluation of an Enzyme-Linked Viral Inducible System for the Rapid Detection of Herpes Simplex Virus [Elektronische Daten] [M. T. LaRocco]  A commercial enzyme-linked viral inducible system (ELVIS HSV; BioWhittaker, USA) was evaluated in comparison with the spin-amplified tube cell culture (SATCC) method for the rapid detection of herpes simplex virus in 1007 clinical specimens. A total of 91 (9%) specimens were positive by SATCC. The sensitivity, specificity, positive predictive value, and negative predictive value of ELVIS was 88%, >99%, 99%, and 99%, respectively. Herpes simplex virus was detected sooner by ELVIS than by SATCC in 34 of 80 (42%) specimens. Preincubated ELVIS shell vials held at room temperature for 24 h prior to reincubation and inoculation produced results similar to those of freshly preincubated shell vials, with no reduction in either the number or the staining intensity of the infected cells. The results of this study indicate that ELVIS HSV is an accurate method for the rapid detection of herpes simplex virus in a wide variety of clinical specimens. Springer-Verlag Berlin Heidelberg, 2000 https://doi.org/10.1007/s100960050466 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s100960050466 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- LaRocco M. T. Department of Pathology, St. Luke's Episcopal Hospital, PO Box 20269, M.C. 4-265, Houston, TX 77225-0269, USA e-mail: mlarocco@sleh.com, US aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer