caa a22 4500 475832043 CHVBK 20180406123842.0 cr unu---uuuuu 170329e20001101xx s 000 0 eng 10.1007/s100960000361 doi (NATIONALLICENCE)springer-10.1007/s100960000361 Prognostic Factors for Pneumococcal Bacteremia in a University Hospital [Elektronische Daten] [C. Fariñas Alvarez, M. C. Fariñas, J. D. García-Palomo, M. González-Ruiz, C. Fernández Mazarrasa, J. A. Parra, J. González-Macías]  The records of adult patients with pneumococcal bacteremia who were seen over an 8-year-period at an 1100-bed university teaching hospital were reviewed in order to revise the clinical and laboratory findings and to identify the risk factors associated with mortality. A total of 156 patients were studied, 101 men and 55 women. The mean age of the patients was 65 years. Eighty-seven percent of the patients had community-acquired bacteremia and 13% had nosocomial pneumococcal bacteremia. The overall mortality was 33.9% and the related mortality was 20.5%. The following factors were associated with an increased risk of adverse outcome in the univariate analysis: mechanical ventilation (risk ratio [RR]=3.40; 95% confidence interval [95% CI]=1.44-8.05), administration of parenteral nutrition (RR=3.40; 95% CI=1.44-8.05), and the presence of an intravenous catheter (RR=2.33; 95% CI=1.27-4.24). In the multivariate analysis, the independent prognostic factors for mortality were as follows: development of clinical complications during the episode of bacteremia, rapidly fatal illness, advanced age and administration of parenteral nutrition. The results suggest that the overall mortality due to pneumococcal bacteremia continues to be high. Four independent risk factors associated with increased mortality were identified. Prevention and immunization with polyvalent pneumococcal polysaccharide vaccine should be practiced more widely. Springer-Verlag Berlin Heidelberg, 2000 Fariñas Alvarez C. Division of Preventive Medicine and Public Health, University of Cantabria School of Medicine, Santander, Spain, ES aut Fariñas M. C. Infectious Diseases Unit, Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain e-mail: mirfac@humv.es Tel.: +34-942-20-33-75; Fax: +34-942-20-26-60, ES aut García-Palomo J. D. Infectious Diseases Unit, Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain e-mail: mirfac@humv.es Tel.: +34-942-20-33-75; Fax: +34-942-20-26-60, ES aut González-Ruiz M. Infectious Diseases Unit, Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain e-mail: mirfac@humv.es Tel.: +34-942-20-33-75; Fax: +34-942-20-26-60, ES aut Fernández Mazarrasa C. Service of Microbiology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, ES aut Parra J. A. Service of Radiology, Hospital Sierrallana, Torrelavega, Spain, ES aut González-Macías J. Infectious Diseases Unit, Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain e-mail: mirfac@humv.es Tel.: +34-942-20-33-75; Fax: +34-942-20-26-60, ES aut https://doi.org/10.1007/s100960000361 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s100960000361 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fariñas Alvarez C. Division of Preventive Medicine and Public Health, University of Cantabria School of Medicine, Santander, Spain, ES aut NATIONALLICENCE 700 1- Fariñas M. C. Infectious Diseases Unit, Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain e-mail: mirfac@humv.es Tel.: +34-942-20-33-75; Fax: +34-942-20-26-60, ES aut NATIONALLICENCE 700 1- García-Palomo J. D. Infectious Diseases Unit, Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain e-mail: mirfac@humv.es Tel.: +34-942-20-33-75; Fax: +34-942-20-26-60, ES aut NATIONALLICENCE 700 1- González-Ruiz M. Infectious Diseases Unit, Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain e-mail: mirfac@humv.es Tel.: +34-942-20-33-75; Fax: +34-942-20-26-60, ES aut NATIONALLICENCE 700 1- Fernández Mazarrasa C. Service of Microbiology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, ES aut NATIONALLICENCE 700 1- Parra J. A. Service of Radiology, Hospital Sierrallana, Torrelavega, Spain, ES aut NATIONALLICENCE 700 1- González-Macías J. Infectious Diseases Unit, Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain e-mail: mirfac@humv.es Tel.: +34-942-20-33-75; Fax: +34-942-20-26-60, ES aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer