caa a22 4500 475832086 CHVBK 20180406123842.0 cr unu---uuuuu 170329e20001101xx s 000 0 eng 10.1007/s100960000366 doi (NATIONALLICENCE)springer-10.1007/s100960000366 cagA , vacA and iceA Virulence Genes of Helicobacter pylori Isolates of Children in Finland [Elektronische Daten] [J. Karhukorpi, Y. Yan, K.-L. Kolho, H. Rautelin, M. Lahti, A. Sirviö, K. Riipinen, H. Lindahl, M. Verkasalo, R. Fagerholm, R. Karttunen]  cagA, vacA s and m genotypes and iceA alleles were analyzed from Helicobacter pylori strains isolated from 17 Finnish children and 32 children of non-Finnish origin living in Finland. Twelve children in the latter group were eastern European and 15 were of African origin. Only three children of non-Finnish origin were born in Finland. The vacA s1a subtype was more prevalent in the isolates from Finnish children than African children (76% vs. 7%, P<0.001);vacA s1b frequencies were 5% and 67%, respectively (P<0.001). The iceA1 allele was significantly more prevalent in African than Finnish isolates (93% vs. 35%, P<0.01). Considerable variation was noted in the frequency of vacA s1 subtypes and iceA alleles in children originating from different geographic regions, but the geographic variation of s1 subtypes resembled that described in other reports. Springer-Verlag Berlin Heidelberg, 2000 Karhukorpi J. Department of Medical Microbiology, University of Oulu, PL 5000, 90014, Oulu, Finland e-mail: Jari.Karhukorpi@oulu.fi, Fax: +358-8-335908, FI aut Yan Y. Department of Medical Microbiology, University of Oulu, PL 5000, 90014, Oulu, Finland e-mail: Jari.Karhukorpi@oulu.fi, Fax: +358-8-335908, FI aut Kolho K.-L Hospital for Children and Adolescents, Helsinki University Central Hospital, Helsinki, Finland, FI aut Rautelin H. Department of Bacteriology and Immunology, University of Helsinki and Helsinki University Central Hospital Diagnostics, Helsinki, Finland, FI aut Lahti M. Department of Medical Microbiology, University of Oulu, PL 5000, 90014, Oulu, Finland e-mail: Jari.Karhukorpi@oulu.fi, Fax: +358-8-335908, FI aut Sirviö A. Department of Medical Microbiology, University of Oulu, PL 5000, 90014, Oulu, Finland e-mail: Jari.Karhukorpi@oulu.fi, Fax: +358-8-335908, FI aut Riipinen K. Department of Medical Microbiology, University of Oulu, PL 5000, 90014, Oulu, Finland e-mail: Jari.Karhukorpi@oulu.fi, Fax: +358-8-335908, FI aut Lindahl H. Hospital for Children and Adolescents, Helsinki University Central Hospital, Helsinki, Finland, FI aut Verkasalo M. Hospital for Children and Adolescents, Helsinki University Central Hospital, Helsinki, Finland, FI aut Fagerholm R. Jorvi Hospital, Espoo, Finland, FI aut Karttunen R. Department of Medical Microbiology, University of Oulu, PL 5000, 90014, Oulu, Finland e-mail: Jari.Karhukorpi@oulu.fi, Fax: +358-8-335908, FI aut https://doi.org/10.1007/s100960000366 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s100960000366 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Karhukorpi J. Department of Medical Microbiology, University of Oulu, PL 5000, 90014, Oulu, Finland e-mail: Jari.Karhukorpi@oulu.fi, Fax: +358-8-335908, FI aut NATIONALLICENCE 700 1- Yan Y. Department of Medical Microbiology, University of Oulu, PL 5000, 90014, Oulu, Finland e-mail: Jari.Karhukorpi@oulu.fi, Fax: +358-8-335908, FI aut NATIONALLICENCE 700 1- Kolho K.-L Hospital for Children and Adolescents, Helsinki University Central Hospital, Helsinki, Finland, FI aut NATIONALLICENCE 700 1- Rautelin H. Department of Bacteriology and Immunology, University of Helsinki and Helsinki University Central Hospital Diagnostics, Helsinki, Finland, FI aut NATIONALLICENCE 700 1- Lahti M. Department of Medical Microbiology, University of Oulu, PL 5000, 90014, Oulu, Finland e-mail: Jari.Karhukorpi@oulu.fi, Fax: +358-8-335908, FI aut NATIONALLICENCE 700 1- Sirviö A. Department of Medical Microbiology, University of Oulu, PL 5000, 90014, Oulu, Finland e-mail: Jari.Karhukorpi@oulu.fi, Fax: +358-8-335908, FI aut NATIONALLICENCE 700 1- Riipinen K. Department of Medical Microbiology, University of Oulu, PL 5000, 90014, Oulu, Finland e-mail: Jari.Karhukorpi@oulu.fi, Fax: +358-8-335908, FI aut NATIONALLICENCE 700 1- Lindahl H. Hospital for Children and Adolescents, Helsinki University Central Hospital, Helsinki, Finland, FI aut NATIONALLICENCE 700 1- Verkasalo M. Hospital for Children and Adolescents, Helsinki University Central Hospital, Helsinki, Finland, FI aut NATIONALLICENCE 700 1- Fagerholm R. Jorvi Hospital, Espoo, Finland, FI aut NATIONALLICENCE 700 1- Karttunen R. Department of Medical Microbiology, University of Oulu, PL 5000, 90014, Oulu, Finland e-mail: Jari.Karhukorpi@oulu.fi, Fax: +358-8-335908, FI aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer