caa a22 4500 475832205 CHVBK 20180406123843.0 cr unu---uuuuu 170329e20000501xx s 000 0 eng 10.1007/s100960050476 doi (NATIONALLICENCE)springer-10.1007/s100960050476 Prospective Surveillance of Vancomycin-Resistant Enterococci in a Neonatal Intensive Care Unit [Elektronische Daten] [H. Toledano, Y. Schlesinger, D. Raveh, B. Rudensky, D. Attias, A. I. Eidelman, A. M. Yinnon]  A point-prevalence study of vancomycin-resistant enterococci colonization of the gastrointestinal tract in an Israeli hospital revealed that 14.7% of the 320 inpatients were colonized. Vancomycin-resistant enterococci colonization was detected in most departments except the neonatal intensive care unit. Hence, a prospective longitudinal study of the prevalence of vancomycin-resistant enterococci colonization in the neonatal intensive care unit was conducted. A rectal swab was obtained from every newborn on admission to the neonatal intensive care unit and once weekly thereafter until the patient was discharged. Enterococci were isolated and tested for susceptibility to vancomycin. A total of 84 neonates were enrolled and monitored on average for 3 weeks (SD±3.9, range 1-20 weeks). Mean gestational age was 35.7 weeks (SD±3.9, range 25-42 weeks), and mean birth weight was 2.4 kg (SD±0.9, range 0.45-4.1 kg). Most patients had one or more of the known risk factors associated with colonization with vancomycin-resistant enterococci. Eighty percent of the patients received antibiotics during the study, and 14.3% received vancomycin. The median duration of vancomycin treatment was 12.5 days (SD±16.8, range 5-55 days). Fifty-one of 84 (61%) patients acquired enterococci sensitive to vancomycin during the study period, but no newborn had vancomycin-resistant enterococci. Possible explanations for this finding may be physical isolation of the neonatal intensive care unit from the rest of the hospital, intrinsic differences in the bowel milieu of this age group and the lack of exposure to food and other environmental sources of vancomycin-resistant enterococci from the community. Springer-Verlag Berlin Heidelberg, 2000 Toledano H. Department of Pediatrics, Shaare Zedek Medical Center, PO Box 3235, Jerusalem 91031, Israel, IL aut Schlesinger Y. Infectious Disease Unit, Shaare Zedek Medical Center, PO Box 3235, Jerusalem 91031, Israel e-mail: yechiel@szmc.org.il, IL aut Raveh D. Infectious Disease Unit, Shaare Zedek Medical Center, PO Box 3235, Jerusalem 91031, Israel e-mail: yechiel@szmc.org.il, IL aut Rudensky B. Microbiology Laboratory, Shaare Zedek Medical Center, PO Box 3235, Jerusalem 91031, Israel, IL aut Attias D. Microbiology Laboratory, Shaare Zedek Medical Center, PO Box 3235, Jerusalem 91031, Israel, IL aut Eidelman A. I. Department of Neonatology, Shaare Zedek Medical Center, PO Box 3235, Jerusalem, 91031, Israel, IL aut Yinnon A. M. Infectious Disease Unit, Shaare Zedek Medical Center, PO Box 3235, Jerusalem 91031, Israel e-mail: yechiel@szmc.org.il, IL aut https://doi.org/10.1007/s100960050476 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s100960050476 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Toledano H. Department of Pediatrics, Shaare Zedek Medical Center, PO Box 3235, Jerusalem 91031, Israel, IL aut NATIONALLICENCE 700 1- Schlesinger Y. Infectious Disease Unit, Shaare Zedek Medical Center, PO Box 3235, Jerusalem 91031, Israel e-mail: yechiel@szmc.org.il, IL aut NATIONALLICENCE 700 1- Raveh D. Infectious Disease Unit, Shaare Zedek Medical Center, PO Box 3235, Jerusalem 91031, Israel e-mail: yechiel@szmc.org.il, IL aut NATIONALLICENCE 700 1- Rudensky B. Microbiology Laboratory, Shaare Zedek Medical Center, PO Box 3235, Jerusalem 91031, Israel, IL aut NATIONALLICENCE 700 1- Attias D. Microbiology Laboratory, Shaare Zedek Medical Center, PO Box 3235, Jerusalem 91031, Israel, IL aut NATIONALLICENCE 700 1- Eidelman A. I. Department of Neonatology, Shaare Zedek Medical Center, PO Box 3235, Jerusalem, 91031, Israel, IL aut NATIONALLICENCE 700 1- Yinnon A. M. Infectious Disease Unit, Shaare Zedek Medical Center, PO Box 3235, Jerusalem 91031, Israel e-mail: yechiel@szmc.org.il, IL aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer