caa a22 4500 475832574 CHVBK 20180406123844.0 cr unu---uuuuu 170329e20000601xx s 000 0 eng 10.1007/s100960050500 doi (NATIONALLICENCE)springer-10.1007/s100960050500 Distribution of Macrolide-Resistance Genes in Staphylococcus aureus Blood-Culture Isolates from Fifteen German University Hospitals [Elektronische Daten] [F.-J. Schmitz, J. Petridou, A. C. Fluit, U. Hadding, G. Peters, C. von Eiff]  The purpose of the study was to analyze the distribution of the macrolide-resistance genes in 134 erythromycin-resistant Staphylococcus aureus blood-culture isolates collected at 15 German university hospitals. The most prevalent resistance gene was ermC (68/134; 50.7%), followed by ermA (52/134; 38.8%), ereB (10/134; 7.5%), and mrsA/msrB (4/134; 6%). The least common genes were ermB (3/134; 2.2%) and ereA (1/134; 0.7%). Overall, resistance to erythromycin was predominantly due to the presence of two erm genes, although with different distributions, depending on the methicillin-resistance pattern. Springer-Verlag Berlin Heidelberg, 2000 Schmitz F.-J Eijkman-Winkler Institute for Clinical Microbiology, Utrecht Medical Center, University of Utrecht, The Netherlands, NL aut Petridou J. Institute for Medical Microbiology and Virology, Heinrich-Heine-Universität Düsseldorf, Universitätsstraße 1, Geb. 22.21, 40225 Düsseldorf, Germany e-mail: schmitfj@uni-duesseldorf.de, DE aut Fluit A. C. Eijkman-Winkler Institute for Clinical Microbiology, Utrecht Medical Center, University of Utrecht, The Netherlands, NL aut Hadding U. Institute for Medical Microbiology and Virology, Heinrich-Heine-Universität Düsseldorf, Universitätsstraße 1, Geb. 22.21, 40225 Düsseldorf, Germany e-mail: schmitfj@uni-duesseldorf.de, DE aut Peters G. Institute of Medical Microbiology, Westfälische Wilhelms University Münster, Germany, DE aut von Eiff C. Institute of Medical Microbiology, Westfälische Wilhelms University Münster, Germany, DE aut https://doi.org/10.1007/s100960050500 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s100960050500 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Schmitz F.-J Eijkman-Winkler Institute for Clinical Microbiology, Utrecht Medical Center, University of Utrecht, The Netherlands, NL aut NATIONALLICENCE 700 1- Petridou J. Institute for Medical Microbiology and Virology, Heinrich-Heine-Universität Düsseldorf, Universitätsstraße 1, Geb. 22.21, 40225 Düsseldorf, Germany e-mail: schmitfj@uni-duesseldorf.de, DE aut NATIONALLICENCE 700 1- Fluit A. C. Eijkman-Winkler Institute for Clinical Microbiology, Utrecht Medical Center, University of Utrecht, The Netherlands, NL aut NATIONALLICENCE 700 1- Hadding U. Institute for Medical Microbiology and Virology, Heinrich-Heine-Universität Düsseldorf, Universitätsstraße 1, Geb. 22.21, 40225 Düsseldorf, Germany e-mail: schmitfj@uni-duesseldorf.de, DE aut NATIONALLICENCE 700 1- Peters G. Institute of Medical Microbiology, Westfälische Wilhelms University Münster, Germany, DE aut NATIONALLICENCE 700 1- von Eiff C. Institute of Medical Microbiology, Westfälische Wilhelms University Münster, Germany, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer