caa a22 4500 475832647 CHVBK 20180406123844.0 cr unu---uuuuu 170329e20000601xx s 000 0 eng 10.1007/s100960050489 doi (NATIONALLICENCE)springer-10.1007/s100960050489 Management of Brain Abscesses with Sequential Intravenous/Oral Antibiotic Therapy [Elektronische Daten] [A. T. Skoutelis, C. A. Gogos, T. E. Maraziotis, H. P. Bassaris]  Eight patients with brain abscesses who refused prolonged hospitalisation were treated with a short course (6-12 days) of intravenous antibiotics followed by prolonged treatment (15-19 weeks) with an oral antibiotic regimen consisting of metronidazole, ciprofloxacin and amoxicillin. All patients responded favourably as shown clinically and in imaging studies. No severe adverse events or sequelae were noted. On admission all patients had a normal or mildly impaired mental status, abscesses less than 3 cm in diameter and no serious predisposing factors. Although combined surgical/medical treatment remains the standard approach in management of these patients, the findings suggest that oral antibiotic therapy only subsequent to a short course of intravenous antibiotics may be an acceptable alternative in selected cases. Springer-Verlag Berlin Heidelberg, 2000 Skoutelis A. T. Section of Infectious Diseases, Patras University Medical School, University Hospital, 26500 Rio Patra, Greece, GR aut Gogos C. A. Department of Medicine, Patras University Medical School, University Hospital, 26500 Rio Patra, Greece, GR aut Maraziotis T. E. Department of Neurosurgery, Patras, University Medical School, University Hospital, 26500 Rio Patra, Greece, GR aut Bassaris H. P. Section of Infectious Diseases, Patras University Medical School, University Hospital, 26500 Rio Patra, Greece, GR aut https://doi.org/10.1007/s100960050489 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s100960050489 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Skoutelis A. T. Section of Infectious Diseases, Patras University Medical School, University Hospital, 26500 Rio Patra, Greece, GR aut NATIONALLICENCE 700 1- Gogos C. A. Department of Medicine, Patras University Medical School, University Hospital, 26500 Rio Patra, Greece, GR aut NATIONALLICENCE 700 1- Maraziotis T. E. Department of Neurosurgery, Patras, University Medical School, University Hospital, 26500 Rio Patra, Greece, GR aut NATIONALLICENCE 700 1- Bassaris H. P. Section of Infectious Diseases, Patras University Medical School, University Hospital, 26500 Rio Patra, Greece, GR aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer