caa a22 4500 475832701 CHVBK 20180406123844.0 cr unu---uuuuu 170329e20000601xx s 000 0 eng 10.1007/s100960050493 doi (NATIONALLICENCE)springer-10.1007/s100960050493 Response to Replacement Iron Therapy in Sideropenic Individuals with Recrudescent Herpes Labialis [Elektronische Daten] [A. Willis, P. Hyland, P.-J. Lamey]  This study investigated the effects of iron replacement on the incidence of recurrent herpes labialis and serum ferritin levels in patients with sideropenia. Ten patients with diagnosed sideropenia and a history of recrudescent herpes labialis were prescribed ferrous sulphate for a period of 3 months. Patients were questioned on the number of episodes of recrudescent herpes labialis that developed per month before treatment and the number of episodes of recrudescent herpes labialis that developed per month after the commencement of replacement iron therapy and during the follow-up period. All blood samples were collected by venipuncture for assay of ferritin levels. Serum ferritin levels were significantly increased compared to pretreatment levels (P<0.05). The number of monthly episodes of recrudescent herpes labialis was reduced from 0.78 to 0.2 episodes per month following treatment (P<0.05). The findings of this study suggest that iron replacement therapy should be further studied as a treatment option in sideropenic individuals with frequent recurrences of recrudescent herpes labialis. Springer-Verlag Berlin Heidelberg, 2000 Willis A. Department of Oral Surgery, Oral Medicine & Oral Pathology, School of Clinical Dentistry, The Queen's University of Belfast, Grosvenor Road, Belfast BT12 6BP, Northern Ireland e-mail: a.willis@qub.ac.uk, IE aut Hyland P. Department of Oral Surgery, Oral Medicine & Oral Pathology, School of Clinical Dentistry, The Queen's University of Belfast, Grosvenor Road, Belfast BT12 6BP, Northern Ireland e-mail: a.willis@qub.ac.uk, IE aut Lamey P.-J Department of Oral Surgery, Oral Medicine & Oral Pathology, School of Clinical Dentistry, The Queen's University of Belfast, Grosvenor Road, Belfast BT12 6BP, Northern Ireland e-mail: a.willis@qub.ac.uk, IE aut https://doi.org/10.1007/s100960050493 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s100960050493 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Willis A. Department of Oral Surgery, Oral Medicine & Oral Pathology, School of Clinical Dentistry, The Queen's University of Belfast, Grosvenor Road, Belfast BT12 6BP, Northern Ireland e-mail: a.willis@qub.ac.uk, IE aut NATIONALLICENCE 700 1- Hyland P. Department of Oral Surgery, Oral Medicine & Oral Pathology, School of Clinical Dentistry, The Queen's University of Belfast, Grosvenor Road, Belfast BT12 6BP, Northern Ireland e-mail: a.willis@qub.ac.uk, IE aut NATIONALLICENCE 700 1- Lamey P.-J Department of Oral Surgery, Oral Medicine & Oral Pathology, School of Clinical Dentistry, The Queen's University of Belfast, Grosvenor Road, Belfast BT12 6BP, Northern Ireland e-mail: a.willis@qub.ac.uk, IE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer