caa a22 4500 47583285X CHVBK 20180406123845.0 cr unu---uuuuu 170329e20000301xx s 000 0 eng 10.1007/s100960050437 doi (NATIONALLICENCE)springer-10.1007/s100960050437 Risk Factors for Esophageal Candidiasis [Elektronische Daten] [A. Chocarro Martínez, F. Galindo Tobal, G. Ruiz-Irastorza, A. González López, F. Alvarez Navia, C. Ochoa Sangrador, M.I. Martín Arribas]  The role of gastric acid inhibitors as predisposing factors for Candida esophagitis is unknown. A retrospective case-control study of esophageal candidiasis was conducted in human immunodeficiency virus (HIV)-negative patients diagnosed from January 1991 to December 1997. The diagnosis of esophageal candidiasis was always made on the basis of endoscopic and histological criteria. Fifty-one patients were diagnosed with esophageal candidiasis, 15 of whom had esophageal complaints and 48 of whom suffered from another previous chronic disease (17 had cancer). In addition, 20 patients had previously been treated with antibiotics, 13 with steroids and 14 with omeprazole. In the multivariate analysis, neoplasm (odds ratio, 5.50; 95% confidence interval, 1.94-15.56) and therapy with antibiotics (odds ratio, 11.97; 95% confidence interval, 3.82-37.45), steroids (odds ratio, 35.52; 95% confidence interval, 3.90-324.01) or omeprazole (odds ratio, 18.23; 95% confidence interval, 4.67-71.03) were all associated with esophageal candidiasis. These data suggest that Candida esophagitis tends to occur in patients with chronic diseases, most of whom have been previously treated with antibiotics, steroids or omeprazole. The findings support the hypothesis that treatment with omeprazole favors the development of esophageal candidiasis. Springer-Verlag Berlin Heidelberg, 2000 Chocarro Martínez A. Department of Internal Medicine, Hospital "Virgen de la Concha", Avenida de Requejo 31-33, 49022 Zamora, Spain e-mail: achocarrom@medynet.com, ES aut Galindo Tobal F. Department of Internal Medicine, Hospital "Virgen de la Concha", Avenida de Requejo 31-33, 49022 Zamora, Spain e-mail: achocarrom@medynet.com, ES aut Ruiz-Irastorza G. Department of Internal Medicine, Hospital de Mendaro, Mendaro, Guipúzcoa, Spain, ES aut González López A. Department of Internal Medicine, Hospital "Virgen de la Concha", Avenida de Requejo 31-33, 49022 Zamora, Spain e-mail: achocarrom@medynet.com, ES aut Alvarez Navia F. Department of Internal Medicine, Hospital "Virgen de la Concha", Avenida de Requejo 31-33, 49022 Zamora, Spain e-mail: achocarrom@medynet.com, ES aut Ochoa Sangrador C. Unit of Research, Hospital "Virgen de la Concha", Avenida de Requejo 31-33, 49022 Zamora, Spain, ES aut Martín Arribas M.I. Department of Internal Medicine, Hospital "Virgen de la Concha", Avenida de Requejo 31-33, 49022 Zamora, Spain e-mail: achocarrom@medynet.com, ES aut https://doi.org/10.1007/s100960050437 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s100960050437 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chocarro Martínez A. Department of Internal Medicine, Hospital "Virgen de la Concha", Avenida de Requejo 31-33, 49022 Zamora, Spain e-mail: achocarrom@medynet.com, ES aut NATIONALLICENCE 700 1- Galindo Tobal F. Department of Internal Medicine, Hospital "Virgen de la Concha", Avenida de Requejo 31-33, 49022 Zamora, Spain e-mail: achocarrom@medynet.com, ES aut NATIONALLICENCE 700 1- Ruiz-Irastorza G. Department of Internal Medicine, Hospital de Mendaro, Mendaro, Guipúzcoa, Spain, ES aut NATIONALLICENCE 700 1- González López A. Department of Internal Medicine, Hospital "Virgen de la Concha", Avenida de Requejo 31-33, 49022 Zamora, Spain e-mail: achocarrom@medynet.com, ES aut NATIONALLICENCE 700 1- Alvarez Navia F. Department of Internal Medicine, Hospital "Virgen de la Concha", Avenida de Requejo 31-33, 49022 Zamora, Spain e-mail: achocarrom@medynet.com, ES aut NATIONALLICENCE 700 1- Ochoa Sangrador C. Unit of Research, Hospital "Virgen de la Concha", Avenida de Requejo 31-33, 49022 Zamora, Spain, ES aut NATIONALLICENCE 700 1- Martín Arribas M.I. Department of Internal Medicine, Hospital "Virgen de la Concha", Avenida de Requejo 31-33, 49022 Zamora, Spain e-mail: achocarrom@medynet.com, ES aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer