caa a22 4500 475832892 CHVBK 20180406123845.0 cr unu---uuuuu 170329e20000301xx s 000 0 eng 10.1007/s100960050439 doi (NATIONALLICENCE)springer-10.1007/s100960050439 Antimicrobial Resistance Trends in Shigella Serogroups Isolated in Israel, 1990-1995 [Elektronische Daten] [A. Mates, D. Eyny, S. Philo]  From a total of 31 319 Shigella strains isolated in Israel between 1990 and 1996, 17 574 were sent to the National Shigella Reference Center for typing. Of these, 15 287 were identified as Shigella sonnei, 1833 as Shigella flexneri, 327 as Shigella boydii and 127 as Shigella dysenteriae. In all, 4395 strains were tested for sensitivity to ampicillin, trimethoprim-sulfamethoxazole, tetracycline, chloramphenicol, nalidixic acid and ofloxacin. All strains tested were sensitive to ofloxacin, and only three strains were resistant to nalidixic acid. Only 113 of 3240 (3.5%) Shigella sonnei strains, 172 of 970 (17.7%) Shigella flexneri strains and 45 of 185 (24.3%) Shigella boydii strains tested were sensitive to four other antibiotic agents. The rates of resistance of Shigella sonnei, Shigella flexneri and Shigella boydii to trimethoprim-sulfamethoxazole were 94.4%, 51.3% and 61.6%, respectively. Rates of resistance to ampicillin among these species were 73.4%, 63.5% and 21.4%, respectively. The proportion of strains exhibiting multiple drug resistance was higher for Shigella sonnei than for the other serotypes studied. These results emphasize the need to reassess the use of antibiotic agents in the treatment of shigellosis. Springer-Verlag Berlin Heidelberg, 2000 Mates A. Department of Laboratories, Ministry of Health, POB 34410, Jerusalem 91342, Israel e-mail: lbdabraham@matat.health.gov.il, IL aut Eyny D. Public Health Laboratory, POB 8255, Tel-Aviv, Israel, IL aut Philo S. Public Health Laboratory, POB 8255, Tel-Aviv, Israel, IL aut https://doi.org/10.1007/s100960050439 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s100960050439 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mates A. Department of Laboratories, Ministry of Health, POB 34410, Jerusalem 91342, Israel e-mail: lbdabraham@matat.health.gov.il, IL aut NATIONALLICENCE 700 1- Eyny D. Public Health Laboratory, POB 8255, Tel-Aviv, Israel, IL aut NATIONALLICENCE 700 1- Philo S. Public Health Laboratory, POB 8255, Tel-Aviv, Israel, IL aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer