caa a22 4500 475835476 CHVBK 20180406123851.0 cr unu---uuuuu 170329e20001101xx s 000 0 eng 10.1023/A:1010435915430 doi (NATIONALLICENCE)springer-10.1023/A:1010435915430 Role of Neuronal Cell Adhesion Molecules and N-Cadherin in Passive Avoidance Training of Rats [Elektronische Daten] [D. Zhernosekov, P. Nerush] A comparative study of the role of specific adhesion proteins, NCAM (neuronal cell adhesion molecules) and N-cadherin, was carried out on rats subjected to passive avoidance training procedure. It was shown that antibodies against the Ca2+-dependent adhesion protein N-cadherin injected into the rat somatosensory cortical zone 6 h after passive avoidance training had been completed did not evoke a loss of the habit by experimental animals. At the same time, an absolute amnestic effect with respect to this reflex developed after injection of antibodies against NCAM. After injection of antibodies against the above-mentioned proteins into the dorsal part of the hippocampus, the avoidance habit also disappeared in the case of treatment with antibodies against NCAM and was kept under the influence of antibodies against N-cadherin. The data obtained testify that NCAM and N-cadherin play dissimilar roles in the formation of a memory trace in the course of training. Plenum Publishing Corporation, 2000 NCAM nationallicence N-cadherin nationallicence neocortex nationallicence hippocampus nationallicence processes of memory formation nationallicence amnesia nationallicence Zhernosekov D. Dnepropetrovsk State University, Ukraine aut Nerush P. Dnepropetrovsk State Medical Academy, Ministry of Public Health of Ukraine, Ukraine aut Neurophysiology Kluwer Academic Publishers-Plenum Publishers 32/6(2000-11-01), 368-370 0090-2977 32:6<368 2000 32 11062 https://doi.org/10.1023/A:1010435915430 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1010435915430 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zhernosekov D. Dnepropetrovsk State University, Ukraine aut NATIONALLICENCE 700 1- Nerush P. Dnepropetrovsk State Medical Academy, Ministry of Public Health of Ukraine, Ukraine aut NATIONALLICENCE 773 0- Neurophysiology Kluwer Academic Publishers-Plenum Publishers 32/6(2000-11-01), 368-370 0090-2977 32:6<368 2000 32 11062 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer