caa a22 4500 475836316 CHVBK 20180406123854.0 cr unu---uuuuu 170329e20000901xx s 000 0 eng 10.1023/A:1010375523541 doi (NATIONALLICENCE)springer-10.1023/A:1010375523541 Sushko B. Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine aut Effects of Vasopressin and Stimulation of the N. Trigeminus on the Respiratory Activity Generated by Isolated Medullo-Spinal Preparations of Early Postnatal Rats [Elektronische Daten] [B. Sushko] In experiments on isolated medullo-spinal preparations from 2- to 3-day-old rats, we recorded the spontaneous phasic respiratory activity (RA) from filaments of the ventral spinal C 1-C 4 roots and studied modifications of this activity after applications of vasopressin and electrical stimulation of the n. trigeminus. Vasopressin added to the superfusate in minute concentrations (threshold concentration about 1 nM) increased the frequency of the phasic RA; higher concentrations (100 nM or more) induced the development of a tonic activity in the cervical ventral roots. Electrical stimulation of the n. trigeminus by a series of threshold current pulses inhibited the development of the next in turn RA volleys; similar stimulation, but applied in the course of vasopressin application, resulted in generation of inspiratory volleys in response to each stimulating series. The mechanisms of facilitative influences of vasopressin on the RA generation and effects evoked by trigeminal stimulation are discussed. Plenum Publishing Corporation, 2000 isolated medullo-spinal preparation nationallicence respiratory activity nationallicence n. trigeminus nationallicence vasopressin nationallicence Neurophysiology Kluwer Academic Publishers-Plenum Publishers 32/5(2000-09-01), 333-338 0090-2977 32:5<333 2000 32 11062 https://doi.org/10.1023/A:1010375523541 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1010375523541 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Sushko B. Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine aut NATIONALLICENCE 773 0- Neurophysiology Kluwer Academic Publishers-Plenum Publishers 32/5(2000-09-01), 333-338 0090-2977 32:5<333 2000 32 11062 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer