caa a22 4500 475842731 CHVBK 20180406123905.0 cr unu---uuuuu 170329e20000501xx s 000 0 eng 10.1007/s101400050093 doi (NATIONALLICENCE)springer-10.1007/s101400050093 Evaluation of various methods of intravenous contrast enhancement for thoraco-abdominal spiral CT scanning in trauma patients [Elektronische Daten] [K. L. Killeen, D. J. Markert, C. D. Sherbourne, K. Shanmuganathan, S. E. Mirvis, S. P. Murray] The purpose of this study was to determine the optimal contrast concentration, volume, and injection rate for helical CT imaging of trauma patients requiring evaluation of the chest, abdomen, and pelvis. Two hundred forty patients were randomized into six different regimen groups for administration of iohexol nonionic intravenous contrast medium, each regimen containing 36 g iodine, with various injection rates, volumes, and concentrations of intravenous contrast enhancement. Parenchymal and vascular enhancement was objectively measured by obtaining pre- and post-contrast attenuation values of the thoracic and abdominal aorta, liver, and spleen, as well as post-contrast attenuation values of vascular enhancement of the portal vein and iliac artery. The contrast-enhanced images were subjectively reviewed by four radiologists blinded to the contrast administration techniques and objective evaluation results. It was found that while our ability to evaluate the abdominal organs was essentially equivalent with all six contrast administration regimens, our ability to evaluate the thoracic aorta was significantly better using 150 ml iohexol (Omnipaque 240) at 3 ml/s than with the other methods. Therefore, we recommend the use of 150 ml iohexol (Omnipaque 240) at 3 ml/s for combined chest and abdominal studies in patients with blunt trauma. American Society of Emergency Radiology, 2000 Key words Computed tomography , contrast media - Contrast media, comparative studies - Trauma nationallicence Killeen K. L. Department of Diagnostic Radiology, Shock Trauma Center, University of Maryland Medical System, 22 South Greene Street, Baltimore, MD 21201-1595, USA e-mail: KKILL001@umaryland.edu Tel.: + 1-4 10-3 28 65 41 Fax: + 1-4 10-3 28 06 41, US aut Markert D. J. Department of Diagnostic Radiology, Shock Trauma Center, University of Maryland Medical System, 22 South Greene Street, Baltimore, MD 21201-1595, USA e-mail: KKILL001@umaryland.edu Tel.: + 1-4 10-3 28 65 41 Fax: + 1-4 10-3 28 06 41, US aut Sherbourne C. D. Department of Radiology, Southwestern Medical Center, University of Texas, Dallas, Texas, USA, US aut Shanmuganathan K. Department of Diagnostic Radiology, Shock Trauma Center, University of Maryland Medical System, 22 South Greene Street, Baltimore, MD 21201-1595, USA e-mail: KKILL001@umaryland.edu Tel.: + 1-4 10-3 28 65 41 Fax: + 1-4 10-3 28 06 41, US aut Mirvis S. E. Department of Diagnostic Radiology, Shock Trauma Center, University of Maryland Medical System, 22 South Greene Street, Baltimore, MD 21201-1595, USA e-mail: KKILL001@umaryland.edu Tel.: + 1-4 10-3 28 65 41 Fax: + 1-4 10-3 28 06 41, US aut Murray S. P. Department of Radiology, Madigan Army Medical Center, Tacoma, Washington, USA, US aut https://doi.org/10.1007/s101400050093 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s101400050093 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Killeen K. L. Department of Diagnostic Radiology, Shock Trauma Center, University of Maryland Medical System, 22 South Greene Street, Baltimore, MD 21201-1595, USA e-mail: KKILL001@umaryland.edu Tel.: + 1-4 10-3 28 65 41 Fax: + 1-4 10-3 28 06 41, US aut NATIONALLICENCE 700 1- Markert D. J. Department of Diagnostic Radiology, Shock Trauma Center, University of Maryland Medical System, 22 South Greene Street, Baltimore, MD 21201-1595, USA e-mail: KKILL001@umaryland.edu Tel.: + 1-4 10-3 28 65 41 Fax: + 1-4 10-3 28 06 41, US aut NATIONALLICENCE 700 1- Sherbourne C. D. Department of Radiology, Southwestern Medical Center, University of Texas, Dallas, Texas, USA, US aut NATIONALLICENCE 700 1- Shanmuganathan K. Department of Diagnostic Radiology, Shock Trauma Center, University of Maryland Medical System, 22 South Greene Street, Baltimore, MD 21201-1595, USA e-mail: KKILL001@umaryland.edu Tel.: + 1-4 10-3 28 65 41 Fax: + 1-4 10-3 28 06 41, US aut NATIONALLICENCE 700 1- Mirvis S. E. Department of Diagnostic Radiology, Shock Trauma Center, University of Maryland Medical System, 22 South Greene Street, Baltimore, MD 21201-1595, USA e-mail: KKILL001@umaryland.edu Tel.: + 1-4 10-3 28 65 41 Fax: + 1-4 10-3 28 06 41, US aut NATIONALLICENCE 700 1- Murray S. P. Department of Radiology, Madigan Army Medical Center, Tacoma, Washington, USA, US aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer