caa a22 4500 475843533 CHVBK 20180406123907.0 cr unu---uuuuu 170329e20000401xx s 000 0 eng 10.1023/A:1027215007012 doi (NATIONALLICENCE)springer-10.1023/A:1027215007012 Enantioselective hydrogenation of pyruvate esters in the mesoporous environment of Pt-MCM-41 [Elektronische Daten] [T.J. Hall, J.E. Halder, G.J. Hutchings, R.L. Jenkins, P. Johnston, P. McMorn, P.B. Wells, R.P.K. Wells] Pt-MCM-41 catalysts having loadings of up to 2% Pt have been synthesised using three strategies: (i) direct synthesis from a Pt2+-containing gel, (ii) exchange of Na+ in Al-MCM-41 (containing 8% aluminium) for Pt2+, (iii) exchange of H+ in H-MCM-41 (containing 1% aluminium) for Pt2+. HRTEM confirmed the retention of the mesoporous structure in the active catalysts and gave information on Pt particle size and location. 27Al NMR provided information on the movement of aluminium within the structure during catalyst preparation. Enantioselective hydrogenation of methyl and ethyl pyruvate was catalysed by cinchonidine-modified Pt-MCM-41 at 293 K and elevated hydrogen pressures; performance was compared to that provided by the standard reference catalyst EUROPT-1. Catalysts prepared by strategies (i) and (ii) performed best, giving values of the enantiomeric excess comparable to those afforded by EUROPT-1 at rates moderated by an order of magnitude by mass transfer effects. Performance was impaired when Pt particle size in the mesopores was so small that conditions favoured racemic reaction. Kluwer Academic Publishers, 2000 enantioselective hydrogenation nationallicence platinum nationallicence cinchonidine nationallicence catalyst modifier nationallicence pyruvate hydrogenation nationallicence MCM-41 nationallicence Pt-MCM-41 preparation nationallicence Pt-MCM-41 characterisation nationallicence Hall T.J. Department of Chemistry, University of Hull, Hull HU6 7RX, UK aut Halder J.E. Department of Chemistry, University of Hull, Hull HU6 7RX, UK aut Hutchings G.J. Department of Chemistry, University of Cardiff, Cardiff CF10 3TB, UK aut Jenkins R.L. Department of Chemistry, University of Cardiff, Cardiff CF10 3TB, UK aut Johnston P. Department of Chemistry, University of Hull, Hull HU6 7RX, UK aut McMorn P. Department of Chemistry, University of Cardiff, Cardiff CF10 3TB, UK aut Wells P.B. Department of Chemistry, University of Hull, Hull HU6 7RX, UK aut Wells R.P.K. Department of Chemistry, University of Cardiff, Cardiff CF10 3TB, UK aut Topics in Catalysis Kluwer Academic Publishers-Plenum Publishers 11-12/1-4(2000-04-01), 351-357 1022-5528 11-12:1-4<351 2000 11-12 11244 https://doi.org/10.1023/A:1027215007012 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1027215007012 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hall T.J. Department of Chemistry, University of Hull, Hull HU6 7RX, UK aut NATIONALLICENCE 700 1- Halder J.E. Department of Chemistry, University of Hull, Hull HU6 7RX, UK aut NATIONALLICENCE 700 1- Hutchings G.J. Department of Chemistry, University of Cardiff, Cardiff CF10 3TB, UK aut NATIONALLICENCE 700 1- Jenkins R.L. Department of Chemistry, University of Cardiff, Cardiff CF10 3TB, UK aut NATIONALLICENCE 700 1- Johnston P. Department of Chemistry, University of Hull, Hull HU6 7RX, UK aut NATIONALLICENCE 700 1- McMorn P. Department of Chemistry, University of Cardiff, Cardiff CF10 3TB, UK aut NATIONALLICENCE 700 1- Wells P.B. Department of Chemistry, University of Hull, Hull HU6 7RX, UK aut NATIONALLICENCE 700 1- Wells R.P.K. Department of Chemistry, University of Cardiff, Cardiff CF10 3TB, UK aut NATIONALLICENCE 773 0- Topics in Catalysis Kluwer Academic Publishers-Plenum Publishers 11-12/1-4(2000-04-01), 351-357 1022-5528 11-12:1-4<351 2000 11-12 11244 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer