caa a22 4500 475845765 CHVBK 20180406123913.0 cr unu---uuuuu 170329e20000301xx s 000 0 eng 10.1007/PL00000702 doi (NATIONALLICENCE)springer-10.1007/PL00000702 Calcium-regulated protein kinase cascades and their transcription factor targets [Elektronische Daten] [F. H. Cruzalegui, H. Bading*] Abstract.: In the nervous system, calcium signals associated with electrical activation of neurons induce gene transcription that may be important for long-lasting adaptation. The type of transcriptional response is determined by the properties of the calcium signal that include subcellular localisation, amplitude, duration and the physical site of entry. Here we review calcium-regulated protein kinase cascades and discuss potential mechanisms through which they propagate calcium signals to and within the nucleus and control the activity of transcription factors and transcriptional coactivators. Birkhäuser Verlag Basel,, 2000 Key words. Calcium signalling nationallicence gene expression nationallicence transcription factors nationallicence protein kinases nationallicence Cruzalegui F. H. Institute of Cell Signalling, University of Nottingham Medical School, Nottingham NG7 2UH (United Kingdom), GB aut Bading* H. Neurobiology Division, MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH (United Kingdom), GB aut https://doi.org/10.1007/PL00000702 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/PL00000702 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cruzalegui F. H. Institute of Cell Signalling, University of Nottingham Medical School, Nottingham NG7 2UH (United Kingdom), GB aut NATIONALLICENCE 700 1- Bading* H. Neurobiology Division, MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH (United Kingdom), GB aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer