caa a22 4500 475846141 CHVBK 20180406123914.0 cr unu---uuuuu 170329e20000401xx s 000 0 eng 10.1007/PL00000716 doi (NATIONALLICENCE)springer-10.1007/PL00000716 Molecular mimicry: a critical look at exemplary instances in human diseases [Elektronische Daten] [N. R. Rose*, I. R. Mackay] Abstract.: Molecular mimicry, the concept that antigenic determinants of microorganisms resemble antigenic determinants of the host, is frequently cited as a plausible mechanism to account for the association of infection and autoimmune disease. Based on analogous sequences of amino acids or on cross-reactions of monoclonal antibodies, numerous examples of such mimicry have been reported. There are, however, no clear examples of a human disease caused by molecular mimicry. Birkhäuser Verlag Basel,, 2000 Key words. Autoimmunity nationallicence molecular mimicry nationallicence myocarditis nationallicence type 1 diabetes nationallicence Lyme disease nationallicence rheumatoid arthritis nationallicence ankylosing spondylitis nationallicence multiple sclerosis nationallicence Rose* N. R. Department of Pathology and Department of Molecular Microbiology and Infectious Disease, The Johns Hopkins Medical Institutions/E5014, 615 North Wolfe Street, Baltimore (Maryland 21205, USA), e-mail: nrrose@jhsph.edu, US aut Mackay I. R. Department of Biochemistry and Molecular Biology, Monash University, Wellington Road, Clayton, Victoria 3168 (Australia), AU aut https://doi.org/10.1007/PL00000716 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/PL00000716 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rose* N. R. Department of Pathology and Department of Molecular Microbiology and Infectious Disease, The Johns Hopkins Medical Institutions/E5014, 615 North Wolfe Street, Baltimore (Maryland 21205, USA), e-mail: nrrose@jhsph.edu, US aut NATIONALLICENCE 700 1- Mackay I. R. Department of Biochemistry and Molecular Biology, Monash University, Wellington Road, Clayton, Victoria 3168 (Australia), AU aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer