caa a22 4500 475846664 CHVBK 20180406123916.0 cr unu---uuuuu 170329e20000201xx s 000 0 eng 10.1023/A:1008919227665 doi (NATIONALLICENCE)springer-10.1023/A:1008919227665 Health-related quality of life among people with HIV disease: Results from the Multicenter AIDS Cohort Study [Elektronische Daten] [E.G. Bing, R.D. Hays, L.P. Jacobson, B. Chen, S.J. Gange, N.E. Kass, J.S. Chmiel, S.L. Zucconi] To examine the effect of HIV status, symptomatology and CD4+ lymphocyte level on health-related quality of life, the Medical Outcomes Study Short-Form Health Survey (SF-36) was administered to 2,295 gay men enrolled in the Multicenter AIDS Cohort Study (MACS) in 1994. Distinct physical and mental health factors of the SF-36 were found. Seropositive asymptomatic individuals and seropositive individuals with CD4+ lymphocytes ≥ 500/mm3 scored as well as seronegative participants on all of the mental health domain scales, but lower on the general health perceptions and physical health composite score. Seropositive individuals with at least one symptom or with CD4+ lymphocytes below 200/mm3 scored significantly lower on all of the SF-36 scales and summary scores than seronegative controls. The SF-36 was found to exhibit similar mental and physical health factors for an adult gay male population to that previously seen in general population samples and in patient groups with other diseases. In conclusion, HIV-positive men who are asymptomatic or have CD4+ lymphocytes above 500/mm3 have similar perceived mental health but worse perceived physical health than seronegative men. HIV-positive men who are symptomatic or have CD4+ lymphocytes below 200/mm3 have worse perceived mental and physical health than seronegative men. Kluwer Academic Publishers, 2000 Acquired immune deficiency syndrome (AIDS) factor analysis nationallicence Functional status nationallicence Health status nationallicence Health status indicators nationallicence Human immunodeficiency virus (HIV) nationallicence Mental health nationallicence Quality of life nationallicence Bing E.G. Department of Psychiatry, Charles R. Drew University of Medicine & Science, 1774 E. 118th Street, Building K, 90059, Los Angeles, CA, USA aut Hays R.D. RAND, UCLA School of Medicine, USA aut Jacobson L.P. Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, USA aut Chen B. Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, USA aut Gange S.J. Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, USA aut Kass N.E. Program in Law, Ethics, and Health, Johns Hopkins School of Hygiene and Public Health and Bioethics Institute, USA aut Chmiel J.S. Department of Preventive Medicine, Northwestern Univerisity Medical School, USA aut Zucconi S.L. The Nemours Foundation, USA aut Quality of Life Research Kluwer Academic Publishers 9/1(2000-02-01), 55-63 0962-9343 9:1<55 2000 9 11136 https://doi.org/10.1023/A:1008919227665 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1008919227665 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bing E.G. Department of Psychiatry, Charles R. Drew University of Medicine & Science, 1774 E. 118th Street, Building K, 90059, Los Angeles, CA, USA aut NATIONALLICENCE 700 1- Hays R.D. RAND, UCLA School of Medicine, USA aut NATIONALLICENCE 700 1- Jacobson L.P. Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, USA aut NATIONALLICENCE 700 1- Chen B. Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, USA aut NATIONALLICENCE 700 1- Gange S.J. Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, USA aut NATIONALLICENCE 700 1- Kass N.E. Program in Law, Ethics, and Health, Johns Hopkins School of Hygiene and Public Health and Bioethics Institute, USA aut NATIONALLICENCE 700 1- Chmiel J.S. Department of Preventive Medicine, Northwestern Univerisity Medical School, USA aut NATIONALLICENCE 700 1- Zucconi S.L. The Nemours Foundation, USA aut NATIONALLICENCE 773 0- Quality of Life Research Kluwer Academic Publishers 9/1(2000-02-01), 55-63 0962-9343 9:1<55 2000 9 11136 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer