caa a22 4500 475847121 CHVBK 20180406123917.0 cr unu---uuuuu 170329e20001201xx s 000 0 eng 10.1023/A:1016670403148 doi (NATIONALLICENCE)springer-10.1023/A:1016670403148 Re-validation and Shortening of the Functional Assessmentof Anorexia/Cachexia Therapy (FAACT) Questionnaire [Elektronische Daten] [J.M. Ribaudo, D. Cella, E.A. Hahn, S.R. Lloyd, N.S. Tchekmedyian, J. Roenn, W.T. Leslie] Purpose: The original Functional Assessment of Anorexia/Cachexia Therapy (FAACT) was designed to measure general aspects of quality of life (QOL) as well as specific anorexia/cachexia-related concerns. Our primary purpose was to reduce the number of anorexia/cachexia subscale items in a manner that either retains or improves reliability, validity and precision. Methods: The FAACT was administered using an interactive computer program that allowed immediate entry of the data. A total of 213 patients were recruited. Results: A combined empirical and conceptual approach led to the reduction of the anorexia/cachexia subscale (A/CS) from 18 to 12 items. A 26-item trial outcome index (TOI) combining physical well-being (PWB), functional well-being (FWB), and the A/CS-12 was highly reliable and sensitive to change in performance status rating (PSR). We found that PWB, FWB, and A/CS-12 subscales performed differently. Specifically, PWB and FWB scores decreased in patients whose (PSR) worsened. However, although A/CS-12 scores were responsive to change in PSR over time, average A/CS-12 scores of all patients, even those whose PSR worsened, improved over the course of treatment. Conclusions: Elimination of six items from the anorexia/cachexia subscale of the FAACT was accomplished without loss of internal consistency or sensitivity to change in performance status. The A/CS-12 subscale provides unique, important information not captured by a generic chronic illness questionnaire. Kluwer Academic Publishers, 2000 Anorexia/cachexia nationallicence Quality of life nationallicence Scale validation nationallicence Ribaudo J.M. Center on Outcomes Research and Education, Evanston Northwestern Healthcare, Evanston aut Cella D. Center on Outcomes Research and Education, Evanston Northwestern Healthcare, Evanston aut Hahn E.A. Center on Outcomes Research and Education, Evanston Northwestern Healthcare, Evanston aut Lloyd S.R. Center for Conscious Living, Naperville, IL aut Tchekmedyian N.S. Pacific Shores Medical Group, Long Beach, CA aut Roenn J. Section of Hematology/Oncology, Department of Medicine, Northwestern University Medical School, Chicago, IL aut Leslie W.T. Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL, USA aut Quality of Life Research Kluwer Academic Publishers 9/10(2000-12-01), 1137-1146 0962-9343 9:10<1137 2000 9 11136 https://doi.org/10.1023/A:1016670403148 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1016670403148 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ribaudo J.M. Center on Outcomes Research and Education, Evanston Northwestern Healthcare, Evanston aut NATIONALLICENCE 700 1- Cella D. Center on Outcomes Research and Education, Evanston Northwestern Healthcare, Evanston aut NATIONALLICENCE 700 1- Hahn E.A. Center on Outcomes Research and Education, Evanston Northwestern Healthcare, Evanston aut NATIONALLICENCE 700 1- Lloyd S.R. Center for Conscious Living, Naperville, IL aut NATIONALLICENCE 700 1- Tchekmedyian N.S. Pacific Shores Medical Group, Long Beach, CA aut NATIONALLICENCE 700 1- Roenn J. Section of Hematology/Oncology, Department of Medicine, Northwestern University Medical School, Chicago, IL aut NATIONALLICENCE 700 1- Leslie W.T. Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL, USA aut NATIONALLICENCE 773 0- Quality of Life Research Kluwer Academic Publishers 9/10(2000-12-01), 1137-1146 0962-9343 9:10<1137 2000 9 11136 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer