caa a22 4500 475847253 CHVBK 20180406123917.0 cr unu---uuuuu 170329e20000201xx s 000 0 eng 10.1023/A:1008982124694 doi (NATIONALLICENCE)springer-10.1023/A:1008982124694 Development and validation of a quality of life questionnaire for patients with vertebral fractures: Qualeffo-41 [Elektronische Daten] [P. Lips, A. Leplege] Vertebral fractures cause pain and may hamper activities of daily life, mobility, social activities and mental function. These aspects of quality of life may be assessed with a generic or disease-specific quality of life questionnaire. The International Osteoporosis Foundation has developed a specific questionnaire for patients with vertebral fractures. This questionnaire Qualeffo-41, contains 41 questions in the domains pain, physical function, social function, general health perception and mental function. The questionnaire has been translated into many languages. A multicenter validation study showed good repeatability, adequate internal consistency and good discrimination between patients with vertebral fractures and control subjects. Further clinical testing of Qualeffo-41 showed that the domain and total scores increased linearly with the number of prevalent vertebral fractures. Lumbar fractures had more impact on quality of life than thoracic fractures. The impact of vertebral fractures on quality of life increased with age. The results with Qualeffo-41 confirm the decreased quality of life in patients with vertebral fractures. Kluwer Academic Publishers, 2000 Osteoporosis nationallicence Qualeffo nationallicence Quality of life nationallicence Vertebral fractures nationallicence Lips P. Department of Endocrinology, Academic Hospital Vrije Universiteit, PO Box 7057, 1007 MB, Amsterdam, The Netherlands aut Leplege A. INSERM U, 292 Hôpital de Bicêtre, Le Kremlin, Bicêtre Cedex, France aut Quality of Life Research Kluwer Academic Publishers 9(2000-02-01), 763-766 0962-9343 9<763 2000 9 11136 https://doi.org/10.1023/A:1008982124694 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1008982124694 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lips P. Department of Endocrinology, Academic Hospital Vrije Universiteit, PO Box 7057, 1007 MB, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Leplege A. INSERM U, 292 Hôpital de Bicêtre, Le Kremlin, Bicêtre Cedex, France aut NATIONALLICENCE 773 0- Quality of Life Research Kluwer Academic Publishers 9(2000-02-01), 763-766 0962-9343 9<763 2000 9 11136 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer