caa a22 4500 475847431 CHVBK 20180406123918.0 cr unu---uuuuu 170329e20000901xx s 000 0 eng 10.1023/A:1008921419108 doi (NATIONALLICENCE)springer-10.1023/A:1008921419108 Dealing with ceiling baseline treatment satisfaction level in patients with diabetes under flexible, functional insulin treatment: Assessment of improvements in treatment satisfaction with a new insulin analogue [Elektronische Daten] [K. Howorka, J. Pumprla, C. Schlusche, D. Wagner-Nosiska, A. Schabmann, C. Bradley] Even a small improvement in satisfaction with treatment for a chronic disease can be valuable. However, sensitive measurements instruments are needed to assess the effects of treatment changes in patients already well satisfied with baseline treatment. Such instruments were thought to be necessary to deal with ceiling effects in scores of satisfaction with functional insulin treatment (FIT) accommodating full flexibility of food intake and lifestyle in diabetes by manipulation of insulin (FIT; Howorka etal. 2000). The Status(S) version of the Diabetes Treatment Satisfaction Questionnaire (DTSQ, Bradley 1994) was extended with items measuring specific components of FIT and its psychometric properties investigated in a validation study with 171 FIT patients with diabetes. A new Change(C) version of DTSQ extended for FIT was used together with the DTSQ(S) by 52 participants in a subsequent randomised cross-over study involving new fast-acting lispro vs. regular insulin, where treatment satisfaction was the primary outcome variable. Insulin lispro use improved satisfaction (p ≤ 0.001) both, on classical and extended versions of DTSQ(S) and (C), despite high baseline levels of satisfaction. However, the DTSQ(C) augmented the effects of lispro (p = 0.0001) apparent on DTSQ(S) scores and revealed significant treatment effects (p ≤ 0.01) not significant with DTSQ(S). In parallel, glycaemic control improved with lispro (e.g., HbA1c, p = 0.023). Improved satisfaction with treatment was more apparent with DTSQ(C) than DTSQ(S) in patients who at baseline were at or near ceiling for treatment satisfaction. Kluwer Academic Publishers, 2000 Diabetes mellitus nationallicence Functional insulin treatment nationallicence Lifestyle nationallicence Quality of life nationallicence Randomised cross-over study nationallicence Treatment satisfaction nationallicence Howorka K. Research Group on Functional Rehabilitation and Group Education, Institute of Biomedical Engineering and Physics, Austria aut Pumprla J. Research Group on Functional Rehabilitation and Group Education, Institute of Biomedical Engineering and Physics, Austria aut Schlusche C. Research Group on Functional Rehabilitation and Group Education, Institute of Biomedical Engineering and Physics, Austria aut Wagner-Nosiska D. Research Group on Functional Rehabilitation and Group Education, Institute of Biomedical Engineering and Physics, Austria aut Schabmann A. Department of Clinical and Applied Psychology, University of Vienna, Vienna, Austria aut Bradley C. Department of Psychology, Royal Holloway, University of London, Egham, Surrey, UK aut Quality of Life Research Kluwer Academic Publishers 9/8(2000-09-01), 915-930 0962-9343 9:8<915 2000 9 11136 https://doi.org/10.1023/A:1008921419108 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1023/A:1008921419108 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Howorka K. Research Group on Functional Rehabilitation and Group Education, Institute of Biomedical Engineering and Physics, Austria aut NATIONALLICENCE 700 1- Pumprla J. Research Group on Functional Rehabilitation and Group Education, Institute of Biomedical Engineering and Physics, Austria aut NATIONALLICENCE 700 1- Schlusche C. Research Group on Functional Rehabilitation and Group Education, Institute of Biomedical Engineering and Physics, Austria aut NATIONALLICENCE 700 1- Wagner-Nosiska D. Research Group on Functional Rehabilitation and Group Education, Institute of Biomedical Engineering and Physics, Austria aut NATIONALLICENCE 700 1- Schabmann A. Department of Clinical and Applied Psychology, University of Vienna, Vienna, Austria aut NATIONALLICENCE 700 1- Bradley C. Department of Psychology, Royal Holloway, University of London, Egham, Surrey, UK aut NATIONALLICENCE 773 0- Quality of Life Research Kluwer Academic Publishers 9/8(2000-09-01), 915-930 0962-9343 9:8<915 2000 9 11136 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer