caa a22 4500 475848152 CHVBK 20180406123920.0 cr unu---uuuuu 170329e20000701xx s 000 0 eng 10.1007/s004059900206 doi (NATIONALLICENCE)springer-10.1007/s004059900206 Lyme borreliosis, an etiological factor in sensorineural hearing loss? [Elektronische Daten] [M. Peltomaa, Ilmari Pyykkö, Ilkka Seppälä, Lauri Viitanen, Matti Viljanen] The incidence of Lyme borreliosis was studied prospectively in 165 patients with acute idiopathic sensorineural hearing loss. The prevalence of positive levels of antibodies against Borrelia burgdorferi was sixfold higher in patients with sensorineural hearing loss than in the general population in Finland. Four patients fulfilled the criteria for Lyme borreliosis. No specific risk factors were found with which to predict the occurrence of Lyme borreliosis among patients with hearing loss. In logistic regression modeling the poor outcome of hearing loss was best explained by advanced age, high-frequency or flat-type hearing loss, and absence of positive levels of antibodies against B. burgdorferi. Although the causal relationship between Lyme borreliosis and sensorineural hearing loss is difficult to verify, we suggest that Lyme borreliosis is a rare but potentially treatable cause of sudden deafness. We propose that in endemic areas antibodies against Lyme borreliosis should be determined in patients with idiopathic sensorineural hearing loss. Springer-Verlag Berlin Heidelberg, 2000 KeywordsBorrelia burgdorferi nationallicence Lyme borreliosis nationallicence Cranial neuropathy nationallicence Sensorineural hearing loss nationallicence Peltomaa M. Department of Otorhinolaryngology, Helsinki University Central Hospital, Haartmaninkatu 4E, 00290 Helsinki, Finland e-mail: miikka.peltomaa@iki.fi, Tel.: +358-40-5056395, Fax: +358-9-288359, FI aut Pyykkö Ilmari Department of Otorhinolaryngology, Karolinska Hospital, Stockholm, Sweden, SE aut Seppälä Ilkka Division of Bacteriology and Immunology, /HUCH Diagnostics and the Haartman Institute, University of Helsinki, Helsinki, Finland, FI aut Viitanen Lauri Department of Otorhinolaryngology, Helsinki University Central Hospital, Haartmaninkatu 4E, 00290 Helsinki, Finland e-mail: miikka.peltomaa@iki.fi, Tel.: +358-40-5056395, Fax: +358-9-288359, FI aut Viljanen Matti National Public Health Institute, Turku Department, Turku, Finland, FI aut https://doi.org/10.1007/s004059900206 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004059900206 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Peltomaa M. Department of Otorhinolaryngology, Helsinki University Central Hospital, Haartmaninkatu 4E, 00290 Helsinki, Finland e-mail: miikka.peltomaa@iki.fi, Tel.: +358-40-5056395, Fax: +358-9-288359, FI aut NATIONALLICENCE 700 1- Pyykkö Ilmari Department of Otorhinolaryngology, Karolinska Hospital, Stockholm, Sweden, SE aut NATIONALLICENCE 700 1- Seppälä Ilkka Division of Bacteriology and Immunology, /HUCH Diagnostics and the Haartman Institute, University of Helsinki, Helsinki, Finland, FI aut NATIONALLICENCE 700 1- Viitanen Lauri Department of Otorhinolaryngology, Helsinki University Central Hospital, Haartmaninkatu 4E, 00290 Helsinki, Finland e-mail: miikka.peltomaa@iki.fi, Tel.: +358-40-5056395, Fax: +358-9-288359, FI aut NATIONALLICENCE 700 1- Viljanen Matti National Public Health Institute, Turku Department, Turku, Finland, FI aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer