caa a22 4500 475848349 CHVBK 20180406123921.0 cr unu---uuuuu 170329e20001101xx s 000 0 eng 10.1007/s004050000260 doi (NATIONALLICENCE)springer-10.1007/s004050000260 Effect of ethanol on dynamic visual acuity during vertical body oscillation in healthy volunteers [Elektronische Daten] [F. Schmäl, R. Kunz, C. Ortmann, W. Stoll, M. Nieschalk, G. Fechner] Visual orientation is the most important sensory input during locomotion (e.g. walking, driving a car, riding a bicycle). We investigated dynamic visual acuity (DVA) during vertical body-oscillations (amplitude 5 cm; frequency 1.5 Hz) in 12 healthy subjects before and twice after ethanol consumption. During oscillation, vertical eye movements were recorded under two test conditions: with eyes closed (EC) and during DVA testing. A significant increase in vertical eye-amplitude after ethanol ingestion occurred only during EC tests, as a possible sign of vestibular hyperreaction. During vestibular stimulation alone (EC), ethanol did not affect the phase shift between stimulus and eye movements. However, when the subjects were given an additional visual stimulus (DVA), the post-alcohol phase shift rose significantly. Surprisingly, the post-alcohol phase shift values for the two test conditions showed no significant differences. After ethanol ingestion we found no changes in static visual acuity but a significant loss of DVA. Volunteers with a change of DVA threshold (DVAT) showed significantly (P = 0.004) higher post-alcoholic changes in the phase shift. In summary, low doses of ethanol disturbed the visually guided oculomotor response during fixation of an earth-fixed target while the observer was subject to linear vertical acceleration. This effect led to an increasing delay between the beginning of body and eye movements. The consequence was an increasing phase shift and thus a decrease in DVA during whole-body oscillation which was comparable to movements during human locomotion. Springer-Verlag Berlin Heidelberg, 2000 Key words Alcohol nationallicence Dynamic visual acuity nationallicence Vertical linear acceleration nationallicence Maculo-ocular-reflex nationallicence Vertical body-movements nationallicence Schmäl F. Department of Otorhinolaryngology, Head and Neck Surgery, University of Münster, Kardinal-von-Galen-Ring 10, D-48129 Münster, Germany e-mail: schmael.hno@uni-muenster.de, Tel.: +49 251 8356801, Fax: +49 251 8356812, DE aut Kunz R. Department of Otorhinolaryngology, Head and Neck Surgery, University of Münster, Kardinal-von-Galen-Ring 10, D-48129 Münster, Germany e-mail: schmael.hno@uni-muenster.de, Tel.: +49 251 8356801, Fax: +49 251 8356812, DE aut Ortmann C. Department of Legal Medicine, University of Münster, von-Esmarch-Straße 62, D-48149 Münster, Germany, DE aut Stoll W. Department of Otorhinolaryngology, Head and Neck Surgery, University of Münster, Kardinal-von-Galen-Ring 10, D-48129 Münster, Germany e-mail: schmael.hno@uni-muenster.de, Tel.: +49 251 8356801, Fax: +49 251 8356812, DE aut Nieschalk M. Department of Otorhinolaryngology, Head and Neck Surgery, University of Münster, Kardinal-von-Galen-Ring 10, D-48129 Münster, Germany e-mail: schmael.hno@uni-muenster.de, Tel.: +49 251 8356801, Fax: +49 251 8356812, DE aut Fechner G. Department of Legal Medicine, University of Münster, von-Esmarch-Straße 62, D-48149 Münster, Germany, DE aut https://doi.org/10.1007/s004050000260 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004050000260 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Schmäl F. Department of Otorhinolaryngology, Head and Neck Surgery, University of Münster, Kardinal-von-Galen-Ring 10, D-48129 Münster, Germany e-mail: schmael.hno@uni-muenster.de, Tel.: +49 251 8356801, Fax: +49 251 8356812, DE aut NATIONALLICENCE 700 1- Kunz R. Department of Otorhinolaryngology, Head and Neck Surgery, University of Münster, Kardinal-von-Galen-Ring 10, D-48129 Münster, Germany e-mail: schmael.hno@uni-muenster.de, Tel.: +49 251 8356801, Fax: +49 251 8356812, DE aut NATIONALLICENCE 700 1- Ortmann C. Department of Legal Medicine, University of Münster, von-Esmarch-Straße 62, D-48149 Münster, Germany, DE aut NATIONALLICENCE 700 1- Stoll W. Department of Otorhinolaryngology, Head and Neck Surgery, University of Münster, Kardinal-von-Galen-Ring 10, D-48129 Münster, Germany e-mail: schmael.hno@uni-muenster.de, Tel.: +49 251 8356801, Fax: +49 251 8356812, DE aut NATIONALLICENCE 700 1- Nieschalk M. Department of Otorhinolaryngology, Head and Neck Surgery, University of Münster, Kardinal-von-Galen-Ring 10, D-48129 Münster, Germany e-mail: schmael.hno@uni-muenster.de, Tel.: +49 251 8356801, Fax: +49 251 8356812, DE aut NATIONALLICENCE 700 1- Fechner G. Department of Legal Medicine, University of Münster, von-Esmarch-Straße 62, D-48149 Münster, Germany, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer