caa a22 4500 475848373 CHVBK 20180406123921.0 cr unu---uuuuu 170329e20001101xx s 000 0 eng 10.1007/s004050000273 doi (NATIONALLICENCE)springer-10.1007/s004050000273 Uloza V. Department of Otolaryngology, Kaunas University of Medicine, Eiveniu 2, 3007 Kaunas, Lithuania e-mail: inviulo@medi.lt, Fax: +370-7731969, LT aut The course of laryngeal papillomatosis treated by endolaryngeal microsurgery [Elektronische Daten] [V. Uloza] Surgical excision of papillomas remains the mainstay of the management of laryngeal papillomatosis, as causal therapy is not yet available. Eighty-nine patients - 32 with juvenile papillomatosis (JP) and 57 with adult papillomas (AP) - underwent endolaryngeal microsurgery (EM) in our department during the last 15 years. The ENT-department in Kaunas serves most of the patients with laryngeal papilloma among the 3.85 million inhabitants of Lithuania. Therapeutic outcome was assessed as both the recurrence rate and the length of time between recurrences of papillomas in the follow-up period lasting at least 2 years. The recurrence rate was 71.9% (23 patients) in the JP group and 22.8% (13 patients) in the AP group. The interval between recurrences of papillomas ranged from 1 month to 10 years (mean 1.9 years) in the JP group and from 6 months to 9 years (mean 3.2 years) in the AP group. The number of EMs per patient ranged from 1 to 18 (mean 3.2) in the JP group and from 1 to 5 (mean 1.35) in the AP group. EM is a minimally invasive and safe technique which provides accurate removal of papillomas, although recurrence is often unavoidable. Prognosis for the disease therefore remains rather unpredictable. Springer-Verlag Berlin Heidelberg, 2000 Key words Larynx nationallicence Papillomatosis nationallicence Surgery nationallicence https://doi.org/10.1007/s004050000273 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004050000273 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Uloza V. Department of Otolaryngology, Kaunas University of Medicine, Eiveniu 2, 3007 Kaunas, Lithuania e-mail: inviulo@medi.lt, Fax: +370-7731969, LT aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer