caa a22 4500 475848586 CHVBK 20180406123921.0 cr unu---uuuuu 170329e20000401xx s 000 0 eng 10.1007/s004050050206 doi (NATIONALLICENCE)springer-10.1007/s004050050206 Detection of human papillomavirus in cholesteatomas [Elektronische Daten] [W. -Y. Chao, S. -J. Chang, Y. -T. Jin] The presence of human papillomavirus DNA in cholesteatoma may have some role in the development of middle ear cholesteatoma as well as in papilloma. In the present study, polymerase chain reaction and in situ hybridization with human papillomavirus (HPV)-6 and ¶-11 DNA probes were used to detect the presence of HPV DNA in 32 human middle ear cholesteatomas. Only one specimen contained HPV-6 DNA. Although its occurrence may have been coincidental, it is also possible that the hyperproliferative epithelium of cholesteatomas might have some relationship with HPV infections. Springer-Verlag Berlin Heidelberg, 2000 Key words Cholesteatoma nationallicence Middle ear infections nationallicence Human papillomavirus nationallicence Polymerase chain reaction nationallicence In situ hybridization nationallicence Chao W. -Y Department of Otolaryngology, National Cheng Kung University, College of Medicine, 138 Sheng-Li Road, Tainan 70428, Taiwan e-mail: wenyuan@mail.ncku.edu.tw, Tel.: +886 62 76 66 97, Fax: +886 62 09 79 50, TW aut Chang S. -J Department of Biology, National Cheng Kung University, Tainan, Taiwan, TW aut Jin Y. -T Department of Pathology, National Cheng Kung University, Tainan, Taiwan, TW aut https://doi.org/10.1007/s004050050206 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004050050206 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chao W. -Y Department of Otolaryngology, National Cheng Kung University, College of Medicine, 138 Sheng-Li Road, Tainan 70428, Taiwan e-mail: wenyuan@mail.ncku.edu.tw, Tel.: +886 62 76 66 97, Fax: +886 62 09 79 50, TW aut NATIONALLICENCE 700 1- Chang S. -J Department of Biology, National Cheng Kung University, Tainan, Taiwan, TW aut NATIONALLICENCE 700 1- Jin Y. -T Department of Pathology, National Cheng Kung University, Tainan, Taiwan, TW aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer