caa a22 4500 475848799 CHVBK 20180406123922.0 cr unu---uuuuu 170329e20001201xx s 000 0 eng 10.1007/s004050000275 doi (NATIONALLICENCE)springer-10.1007/s004050000275 Primary carcinoma of the subglottic larynx [Elektronische Daten] [R. Santoro, M. Turelli, G. Polli] Primary cancer of the subglottic region is very rare and delay in diagnosis often leads to a poor prognosis. We retrospectively reviewed 49 patients with primary cancer of the subglottic larynx observed from 1969 to 1993 in the ORL Clinic of the University of Florence. This number constitutes 1.6% of all laryngeal cancers observed during this period. Four (8.2%) patients were stage T1, 13 (26.5%) T2, 27 (55.1%) T3, and 5 (10.2%) T4. Forty-one patients were eligible for assessing the disease-free five-year survival rate, 17 of whom were treated with surgery alone, 6 with radiotherapy alone and 18 with combination therapy (surgery for the primary tumor and post-operative radiotherapy for cervical nodes). The five-year survival rate for the three treatment types was 47%, 0% and 83.3%, respectively. The overall survival rate was 56.1%. Combination therapy produced a significantly higher (P = 0.001) disease-free survival than surgery alone or radiotherapy alone. Springer-Verlag Berlin Heidelberg, 2000 Keywords Subglottic larynx nationallicence Combination therapy nationallicence Peristomal recurrences nationallicence Cervical node metastasis nationallicence Santoro R. ORL Clinic Institute, University of Florence, Viale G.B. Morgagni 85, Careggi 50134, Firenze, Italy Tel.: +39-055-411772, Fax: +39-055-435649, IT aut Turelli M. ORL Clinic Institute, University of Florence, Viale G.B. Morgagni 85, Careggi 50134, Firenze, Italy Tel.: +39-055-411772, Fax: +39-055-435649, IT aut Polli G. ORL Clinic Institute, University of Florence, Viale G.B. Morgagni 85, Careggi 50134, Firenze, Italy Tel.: +39-055-411772, Fax: +39-055-435649, IT aut https://doi.org/10.1007/s004050000275 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004050000275 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Santoro R. ORL Clinic Institute, University of Florence, Viale G.B. Morgagni 85, Careggi 50134, Firenze, Italy Tel.: +39-055-411772, Fax: +39-055-435649, IT aut NATIONALLICENCE 700 1- Turelli M. ORL Clinic Institute, University of Florence, Viale G.B. Morgagni 85, Careggi 50134, Firenze, Italy Tel.: +39-055-411772, Fax: +39-055-435649, IT aut NATIONALLICENCE 700 1- Polli G. ORL Clinic Institute, University of Florence, Viale G.B. Morgagni 85, Careggi 50134, Firenze, Italy Tel.: +39-055-411772, Fax: +39-055-435649, IT aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer