caa a22 4500 47584906X CHVBK 20180406123923.0 cr unu---uuuuu 170329e20000901xx s 000 0 eng 10.1007/s004050000257 doi (NATIONALLICENCE)springer-10.1007/s004050000257 Sarcomatoid carcinoma of the pyriform sinus with brain and subcutaneous metastases: an unusual metastatic spread pattern [Elektronische Daten] [D. Hardisson, Juan Ignacio De Diego, María Pilar Prim] A 63-year-old man presented a polypoid tumor in the laryngeal space involving the right pyriform fossa. The patient underwent a total laryngectomy with bilateral functional neck dissection, and the diagnosis of sarcomatoid carcinoma with malignant fibrous histiocytoma-like stroma was established. The tumor showed an uncommon behavior, with distant metastases to the brain and to the subcutaneous tissue of the abdominal wall. The patient died 1 year after the development of the metastases. Despite its polypoid pattern of growth, sarcomatoid carcinoma of the larynx may behave very aggressively. It is important for clinicians to be aware of the possibility of distant subcutaneous and brain metastases in sarcomatoid tumors of the laryngeal space. If such metastases develop, the prognosis is ominous, with an average life expectancy of 3 months. Springer-Verlag Berlin Heidelberg, 2000 Key words Larynx nationallicence Hypopharynx nationallicence Metastases nationallicence Sarcomatoid carcinoma nationallicence Spindle cell carcinoma nationallicence Hardisson D. Departamento de Anatomía Patológica, Hospital Universitario La Paz, Paseo de la Castellana 261, 28046 Madrid, Spain Fax: +34-917277049 e-mail: dhardiss@idecnet.com, ES aut De Diego Juan Ignacio Department of Otorhinolaryngology, La Paz University Hospital, Autonomous University, Madrid, Spain, ES aut Pilar Prim María Department of Otorhinolaryngology, La Paz University Hospital, Autonomous University, Madrid, Spain, ES aut https://doi.org/10.1007/s004050000257 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004050000257 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hardisson D. Departamento de Anatomía Patológica, Hospital Universitario La Paz, Paseo de la Castellana 261, 28046 Madrid, Spain Fax: +34-917277049 e-mail: dhardiss@idecnet.com, ES aut NATIONALLICENCE 700 1- De Diego Juan Ignacio Department of Otorhinolaryngology, La Paz University Hospital, Autonomous University, Madrid, Spain, ES aut NATIONALLICENCE 700 1- Pilar Prim María Department of Otorhinolaryngology, La Paz University Hospital, Autonomous University, Madrid, Spain, ES aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer