caa a22 4500 475849086 CHVBK 20180406123923.0 cr unu---uuuuu 170329e20000501xx s 000 0 eng 10.1007/s004050050234 doi (NATIONALLICENCE)springer-10.1007/s004050050234 Intranasal budesonide spray as an adjunct to oral antibiotic therapy for acute sinusitis in children [Elektronische Daten] [G. Yılmaz, B. Varan, T. Yılmaz, B. Gürakan] We investigated the clinical value of intranasal budesonide in acute sinusitis in 52 children with acute maxillary sinusitis. We randomly divided them into two groups: group 1 received oral pseudoephedrine (2 × 30 mg) and cefaclor (40 mg/kg) for 10 days, and group 2 received intranasal budesonide (2 × 100 μg) and cefaclor (40 mg/kg) for 10 days. Symptoms of headache, cough, and nasal stuffiness and signs of nasal discharge were graded before and after treatment. The patients whose symptoms and signs completely normalized after treatment were considered to have recovered, and those with persisting symptoms and signs after treatment as having not recovered. The results of the two treatment groups were compared. The recovery rate of the children in group 2 were significantly higher than those in group 1 (P < 0.05). No adverse drug effects were determined during the study period. These findings suggest that topical steroids may be a useful adjunctive agent in the treatment of acute sinusitis of children without apparent side effects and can possibly hasten the resolution of symptoms. Springer-Verlag Berlin Heidelberg, 2000 Key words Sinusitis in children nationallicence Topical glucocorticoids nationallicence Yılmaz G. Department of Pediatrics, Başkent University Faculty of Medicine, 12. Sokak, No. 8-7, 06490 Bahçelievler, Ankara, Turkey e-mail: gonca@ato.org.tr, Tel: +90-312-2228365, Fax: +90-312-2127572, TR aut Varan B. Department of Pediatrics, Başkent University Faculty of Medicine, 12. Sokak, No. 8-7, 06490 Bahçelievler, Ankara, Turkey e-mail: gonca@ato.org.tr, Tel: +90-312-2228365, Fax: +90-312-2127572, TR aut Yılmaz T. Department of Otolaryngology, Hacettepe University Faculty of Medicine, 06100 Hacettepe, Ankara, Turkey, TR aut Gürakan B. Department of Pediatrics, Başkent University Faculty of Medicine, 12. Sokak, No. 8-7, 06490 Bahçelievler, Ankara, Turkey e-mail: gonca@ato.org.tr, Tel: +90-312-2228365, Fax: +90-312-2127572, TR aut https://doi.org/10.1007/s004050050234 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004050050234 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yılmaz G. Department of Pediatrics, Başkent University Faculty of Medicine, 12. Sokak, No. 8-7, 06490 Bahçelievler, Ankara, Turkey e-mail: gonca@ato.org.tr, Tel: +90-312-2228365, Fax: +90-312-2127572, TR aut NATIONALLICENCE 700 1- Varan B. Department of Pediatrics, Başkent University Faculty of Medicine, 12. Sokak, No. 8-7, 06490 Bahçelievler, Ankara, Turkey e-mail: gonca@ato.org.tr, Tel: +90-312-2228365, Fax: +90-312-2127572, TR aut NATIONALLICENCE 700 1- Yılmaz T. Department of Otolaryngology, Hacettepe University Faculty of Medicine, 06100 Hacettepe, Ankara, Turkey, TR aut NATIONALLICENCE 700 1- Gürakan B. Department of Pediatrics, Başkent University Faculty of Medicine, 12. Sokak, No. 8-7, 06490 Bahçelievler, Ankara, Turkey e-mail: gonca@ato.org.tr, Tel: +90-312-2228365, Fax: +90-312-2127572, TR aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer