caa a22 4500 475849132 CHVBK 20180406123923.0 cr unu---uuuuu 170329e20000501xx s 000 0 eng 10.1007/s004050050238 doi (NATIONALLICENCE)springer-10.1007/s004050050238 Temporal bone findings in multiple endocrine neoplasia type 2B [Elektronische Daten] [H. Fukaya, C. Suzuki, H. Yasuta, I. Ohtani] To our knowledge, present case is the first published report of temporal bone findings in multiple endocrine neoplasia type 2B (MEN-2B). We describe a 43-year-old Japanese man with medullary thyroid carcinoma (MTC), pheochromocytoma, mucosal neuroma and a Marfanoid body habitus. The collateral adrenal tumors and MTC were removed surgically. However, 14 years after surgery, the MTC and pheochromocytoma recurred and the patient died of intracranial hemorrhage due to hypertension. During the autopsy, metastatic MTC was detected in the liver, lungs, kidneys, pancreas and cervical lymph nodes. Recurrent pheochromocytoma was present in the right kidney. Mucosal neuromas were found in the tongue, gastrointestinal tract and vesical nerve plexus. The following histopathological findings were seen in both temporal bones: metastatic MTC was found as well as neuromas and the cochlear aqueduct was widely patent. Springer-Verlag Berlin Heidelberg, 2000 Key words Multiple endocrine neoplasia nationallicence Mucosal neuroma nationallicence Human temporal bone nationallicence Fukaya H. Department of Otolaryngology, Fukushima Medical University School of Medicine, Fukushima 960-1247, Japan Fax: +81-24-5483011, JP aut Suzuki C. Department of Otolaryngology, Fukushima Medical University School of Medicine, Fukushima 960-1247, Japan Fax: +81-24-5483011, JP aut Yasuta H. Department of Otolaryngology, Fukushima Medical University School of Medicine, Fukushima 960-1247, Japan Fax: +81-24-5483011, JP aut Ohtani I. Department of Otolaryngology, Fukushima Medical University School of Medicine, Fukushima 960-1247, Japan Fax: +81-24-5483011, JP aut https://doi.org/10.1007/s004050050238 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004050050238 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fukaya H. Department of Otolaryngology, Fukushima Medical University School of Medicine, Fukushima 960-1247, Japan Fax: +81-24-5483011, JP aut NATIONALLICENCE 700 1- Suzuki C. Department of Otolaryngology, Fukushima Medical University School of Medicine, Fukushima 960-1247, Japan Fax: +81-24-5483011, JP aut NATIONALLICENCE 700 1- Yasuta H. Department of Otolaryngology, Fukushima Medical University School of Medicine, Fukushima 960-1247, Japan Fax: +81-24-5483011, JP aut NATIONALLICENCE 700 1- Ohtani I. Department of Otolaryngology, Fukushima Medical University School of Medicine, Fukushima 960-1247, Japan Fax: +81-24-5483011, JP aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer