caa a22 4500 475849183 CHVBK 20180406123923.0 cr unu---uuuuu 170329e20000501xx s 000 0 eng 10.1007/s004050050237 doi (NATIONALLICENCE)springer-10.1007/s004050050237 A solitary manifestation of mastocytosis in the head and neck [Elektronische Daten] [E. A. M. Mylanus, E. W. J. Wielinga, J. A. P. van de Nes] Solitary mastocytosis in adulthood is a rare finding. Only two such lesions have been reported in the head and neck. We describe a 27-year-old woman who had a 10-year history of a forehead swelling that had fluctuated in size. Light trauma or pressure on the lesion resulted in an increase in its size. A mass was found to be situated just below the galea and was successfully removed surgically using a high forehead lift. Histologically, the specimen contained predominantly mast cells. A systemic mastocytosis was excluded by a multidisciplinary diagnostic approach and measurement of the 24-h urinary excretion of histamine metabolites. After 36 months of follow-up there has been no recurrence. Springer-Verlag Berlin Heidelberg, 2000 Key words Head and neck solitary lesions nationallicence Mastocytosis nationallicence Histamine nationallicence Surgery nationallicence Mylanus E. A. M. Department of Otorhinolaryngology, University Hospital of Nijmegen, Philips van Leydenlaan 15, Postbus 9101, 6500 HB Nijmegen, The Netherlands Tel.: +31-24-3614450, Fax: +31-24-3540251, NL aut Wielinga E. W. J. Department of Otorhinolaryngology, Free University Hospital of Amsterdam, The Netherlands, NL aut van de Nes J. A. P. Department of Pathology, University Hospital of Nijmegen, Nijmegen, The Netherlands, NL aut https://doi.org/10.1007/s004050050237 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s004050050237 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mylanus E. A. M. Department of Otorhinolaryngology, University Hospital of Nijmegen, Philips van Leydenlaan 15, Postbus 9101, 6500 HB Nijmegen, The Netherlands Tel.: +31-24-3614450, Fax: +31-24-3540251, NL aut NATIONALLICENCE 700 1- Wielinga E. W. J. Department of Otorhinolaryngology, Free University Hospital of Amsterdam, The Netherlands, NL aut NATIONALLICENCE 700 1- van de Nes J. A. P. Department of Pathology, University Hospital of Nijmegen, Nijmegen, The Netherlands, NL aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer