caa a22 4500 477034624 CHVBK 20180405111302.0 cr unu---uuuuu 170330e19960101xx s 000 0 eng 10.1007/s002689900013 doi (NATIONALLICENCE)springer-10.1007/s002689900013 Results of Liver Transplantation for Gastroenteropancreatic Tumor Metastases [Elektronische Daten] [Matthias Anthuber, Karl-Walter Jauch, Josef Briegel, Jochen Groh, Friedrich W. Schildberg] Abstract. During the early 1980s liver transplantation (LTx) was expected to be a promising therapeutic option for patients with primary or secondary tumors confined to the liver. Because of disappointing results owing to death from early recurrence, LTx is currently restricted to well selected patients with small primary tumors and, in the case of liver metastases, to those with metastases of gastroenteropancreatic (GEP) tumor origin only. In our series of 300 liver transplantations four patients with GEP tumor metastases underwent LTx. The primary tumors were one neuroendocrine kidney tumor, one glucagonoma of the pancreas, and two cases of carcinoids of the pancreas. Because of local metastatic lymph node involvement upper gastrointestinal exenteration followed by LTx was performed in two patients. No patient survived beyond 33 months after LTx. Three patients died from tumor recurrence. In one patient who died from fungal sepsis autopsy revealed spine metastases that had been missed before LTx. Our dismal results do not compare well with promising data published previously by others for this particular patient group. Under the pressure of an increasing donor organ shortage, patients with GEP tumor metastases should be selected carefully for LTx.: 1996 by the Société Internationale de Chir, ugie Anthuber Matthias Department of Surgery, University Hospital München-Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany, DE aut Jauch Karl-Walter Department of Surgery, University Hospital München-Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany, DE aut Briegel Josef Institute for Anesthesiology, University Hospital München-Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany, DE aut Groh Jochen Institute for Anesthesiology, University Hospital München-Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany, DE aut Schildberg Friedrich W. Department of Surgery, University Hospital München-Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany, DE aut https://doi.org/10.1007/s002689900013 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689900013 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Anthuber Matthias Department of Surgery, University Hospital München-Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany, DE aut NATIONALLICENCE 700 1- Jauch Karl-Walter Department of Surgery, University Hospital München-Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany, DE aut NATIONALLICENCE 700 1- Briegel Josef Institute for Anesthesiology, University Hospital München-Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany, DE aut NATIONALLICENCE 700 1- Groh Jochen Institute for Anesthesiology, University Hospital München-Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany, DE aut NATIONALLICENCE 700 1- Schildberg Friedrich W. Department of Surgery, University Hospital München-Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer