caa a22 4500 477034640 CHVBK 20180405111302.0 cr unu---uuuuu 170330e19960101xx s 000 0 eng 10.1007/s002689900007 doi (NATIONALLICENCE)springer-10.1007/s002689900007 Subcuticular Skin Closure as a Standard Approach to Emergency Appendectomy in Children: Prospective Clinical Trial [Elektronische Daten] [Francis Serour, Yigal Efrati, Baruch Klin, Joseph Barr, Arkadi Gorenstein, Itzhak Vinograd] Abstract. We evaluated the morbidity associated with primary closure by interrupted subcuticular absorbable sutures following emergency appendectomy. In a prospective clinical trial over a 12-month period, 216 children who underwent emergency appendectomy had skin closure using subcuticular interrupted absorbable polyglactin 4-0 sutures. Preoperative prophylactic antibiotics consisting of metronidazole alone or in combination with gentamicin were used in patients with suspected phlegmonous appendicitis; a combination of metronidazole, gentamicin, and ampicillin was used when perforation of the appendix was suspected. Postoperatively, in patients with phlegmonous appendicitis metronidazole was given for 24 hours, whereas in those with peritonitis the triple antibiotics were continued for 7 to 10 days. All patients were assessed for complications resulting from the technique of wound closure. No intraabdominal abscesses or serious complications were recorded. The overall incidence of wound infection was 1.8%. Among children with a perforated appendix the rate of superficial wound infection was 5.7%. There was no difference in the rate of wound infection between patients who received metronidazole alone or metronidazole plus gentamicin preoperatively. All the patients and their families were satisfied with the cosmetic results and with the fact that removal of skin sutures was unnecessary. We conclude that the use of prophylactic antibiotics permits standard skin closure by interrupted absorbable subcuticular suture.: 1996 by the Société Internationale de Chir, ugie Serour Francis Department of Pediatric Surgery, "Assaf Harofeh” Medical Center, Zerifin 70300, Israel, IL aut Efrati Yigal Department of Pediatric Surgery, "Assaf Harofeh” Medical Center, Zerifin 70300, Israel, IL aut Klin Baruch Department of Pediatric Surgery, "Assaf Harofeh” Medical Center, Zerifin 70300, Israel, IL aut Barr Joseph Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, IL aut Gorenstein Arkadi Division of Pediatric Surgery, The Edith Wolfson Medical Center, Holon 58100, Israel, IL aut Vinograd Itzhak Department of Pediatric Surgery, "Assaf Harofeh” Medical Center, Zerifin 70300, Israel, IL aut https://doi.org/10.1007/s002689900007 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689900007 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Serour Francis Department of Pediatric Surgery, "Assaf Harofeh” Medical Center, Zerifin 70300, Israel, IL aut NATIONALLICENCE 700 1- Efrati Yigal Department of Pediatric Surgery, "Assaf Harofeh” Medical Center, Zerifin 70300, Israel, IL aut NATIONALLICENCE 700 1- Klin Baruch Department of Pediatric Surgery, "Assaf Harofeh” Medical Center, Zerifin 70300, Israel, IL aut NATIONALLICENCE 700 1- Barr Joseph Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, IL aut NATIONALLICENCE 700 1- Gorenstein Arkadi Division of Pediatric Surgery, The Edith Wolfson Medical Center, Holon 58100, Israel, IL aut NATIONALLICENCE 700 1- Vinograd Itzhak Department of Pediatric Surgery, "Assaf Harofeh” Medical Center, Zerifin 70300, Israel, IL aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer