caa a22 4500 477034942 CHVBK 20180405111302.0 cr unu---uuuuu 170330e19961101xx s 000 0 eng 10.1007/s002689900176 doi (NATIONALLICENCE)springer-10.1007/s002689900176 Schwartz Seymour I. Department of Surgery, University of Rochester, School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, New York 14642, U.S.A., US aut Role of Splenectomy in Hematologic Disorders [Elektronische Daten] [Seymour I. Schwartz] Abstract. There has been an increase in the indications for splenectomy for hematologic diseases. It is a consequence of expanding the list of disorders and liberalizing the indications for splenectomy for many diseases. Hereditary spherocytosis is the most frequently encountered congenital anemia for which splenectomy is curative. Splenectomy is generally advised for warm antibody acquired hemolytic anemia if conventional medical therapy fails. Idiopathic thrombocytopenic purpura (ITP) remains the most common hematologic disorder for which splenectomy is therapeutic. A variety of thrombocytopenias are improved by splenectomy. The myeloproliferative disorders constitute a spectrum of disease potentially improved by splenectomy, but preoperative management should be modified in this group. Splenectomy in patients with chronic leukemias and lymphomas are often palliative and facilitate chemotherapy. There are no specific requirements preoperatively other than the administration of pneumoccocal and: Hemophilus influenzae vaccines. Platelets are not administered to patients with ITP. An integral part of the procedure is the search for accessory spleens. The postoperative complication of overwhelming postsplenectomy sepsis must be considered; it occurs more frequently in association with specific basic diseases and can be obviated by appropriate treatment. 1996 by the Société Internationale de Chir, ugie https://doi.org/10.1007/s002689900176 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689900176 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Schwartz Seymour I. Department of Surgery, University of Rochester, School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, New York 14642, U.S.A., US aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer