caa a22 4500 477035353 CHVBK 20180405111303.0 cr unu---uuuuu 170330e19960701xx s 000 0 eng 10.1007/s002689900121 doi (NATIONALLICENCE)springer-10.1007/s002689900121 Surgical Treatment of Graves' Disease in Patients Younger than 18 Years [Elektronische Daten] [Jon-Arne Söreide, Jon A. van Heerden, Chung-Yau Lo, Clive S. Grant, Donald Zimmerman, Duane M. Ilstrup] Abstract. Eighty-two children and adolescents (18 males, 64 females; median age 14 years) surgically treated for Graves' disease at a single institution between 1979 and 1993 were retrospectively reviewed. Most of the patients (74%) coming to thyroidectomy had been treated medically for a period ranging from 2 to 80 (median 15) months. Bilateral subtotal thyroid resection was the most frequently performed procedure (86%). Postoperatively, no permanent recurrent laryngeal nerve palsy or permanent hypocalcemia occurred. Operative mortality was zero. With a median follow-up of 8.3 years, recurrent hyperthyroidism occurred in five patients (6%), one of whom required reoperation. Most children and adolescents with Graves' disease can be rendered euthyroid by nonsurgical treatment options. However, prolonged and ineffective medical treatment should be avoided in these patients who are in the formative years of their lives. Surgical treatment, when indicated and employed, offers young patients with Graves' disease a safe, rapid, definitive, cost-effective treatment with a high success rate.: 1996 by the Société Internationale de Chir, ugie Söreide Jon-Arne Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, U.S.A., US aut van Heerden Jon A. Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, U.S.A., US aut Lo Chung-Yau Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, U.S.A., US aut Grant Clive S. Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, U.S.A., US aut Zimmerman Donald Department of Pediatric and Adolescent Medicine, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, U.S.A., US aut Ilstrup Duane M. Section of Biostatistics, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, Minnesota 55905, U.S.A., US aut https://doi.org/10.1007/s002689900121 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689900121 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Söreide Jon-Arne Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, U.S.A., US aut NATIONALLICENCE 700 1- van Heerden Jon A. Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, U.S.A., US aut NATIONALLICENCE 700 1- Lo Chung-Yau Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, U.S.A., US aut NATIONALLICENCE 700 1- Grant Clive S. Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, U.S.A., US aut NATIONALLICENCE 700 1- Zimmerman Donald Department of Pediatric and Adolescent Medicine, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, U.S.A., US aut NATIONALLICENCE 700 1- Ilstrup Duane M. Section of Biostatistics, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, Minnesota 55905, U.S.A., US aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer