caa a22 4500 477035361 CHVBK 20180405111303.0 cr unu---uuuuu 170330e19960701xx s 000 0 eng 10.1007/s002689900127 doi (NATIONALLICENCE)springer-10.1007/s002689900127 Values of Ultrasonography, Sestamibi Scintigraphy, and Intraoperative Measurement of 1-84 PTH for Unilateral Neck Exploration of Primary Hyperparathyroidism [Elektronische Daten] [Yves Chapuis, Yvonne Fulla, Philippe Bonnichon, Emmanuel Tarla, Bassam Abboud, Jol Pitre, Bruno Richard] Abstract. Unilateral neck exploration (UNE) is a controversial approach to the treatment of primary hyperparathyroidism (PHP), and most surgeons favor bilateral neck exploration. The aim of this study was to assess the value of ultrasonography, sestamibi scintigraphy, and intraoperative measurement of urinary cyclic AMP (UcAMP) or 1-84 PTH in 200 patients undergoing unilateral neck exploration under local anesthesia. Conditions for UNE were (1) a presumed solitary adenoma detected by ultrasonography, (2) no thyroid disease, and (3) no family history of PHP or multiple endocrine neoplasia. Patient's consent was obtained for conversion to bilateral exploration according to surgical and biologic findings. Sensitivity of ultrasonography was 92.5%. Sestamibi scintigraphy, performed in 70 patients, was less sensitive than ultrasonography (80%). Persistent PHP was accurately detected by intraoperative measurement of UcAMP or 1-84 PTH in all cases. At follow-up, 96.0% of the patients were cured either after unilateral neck exploration only (90.5%), or after conversion into bilateral exploration. Ultrasonography and intraoperative measurement of 1-84 PTH allow unilateral neck exploration with excellent results in a selected group of patients with PHP.: 1996 by the Société Internationale de Chir, ugie Chapuis Yves Department of Surgery, Cochin Hospital, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France, FR aut Fulla Yvonne Department of Surgery, Cochin Hospital, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France, FR aut Bonnichon Philippe Department of Surgery, Cochin Hospital, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France, FR aut Tarla Emmanuel Department of Surgery, Cochin Hospital, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France, FR aut Abboud Bassam Department of Surgery, Cochin Hospital, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France, FR aut Pitre Jol Department of Surgery, Cochin Hospital, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France, FR aut Richard Bruno Department of Nuclear Medicine, Cochin Hospital, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France, FR aut https://doi.org/10.1007/s002689900127 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689900127 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chapuis Yves Department of Surgery, Cochin Hospital, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France, FR aut NATIONALLICENCE 700 1- Fulla Yvonne Department of Surgery, Cochin Hospital, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France, FR aut NATIONALLICENCE 700 1- Bonnichon Philippe Department of Surgery, Cochin Hospital, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France, FR aut NATIONALLICENCE 700 1- Tarla Emmanuel Department of Surgery, Cochin Hospital, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France, FR aut NATIONALLICENCE 700 1- Abboud Bassam Department of Surgery, Cochin Hospital, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France, FR aut NATIONALLICENCE 700 1- Pitre Jol Department of Surgery, Cochin Hospital, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France, FR aut NATIONALLICENCE 700 1- Richard Bruno Department of Nuclear Medicine, Cochin Hospital, 27 Rue du Faubourg Saint-Jacques, 75014 Paris, France, FR aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer