caa a22 4500 477035604 CHVBK 20180405111304.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/s002689900052 doi (NATIONALLICENCE)springer-10.1007/s002689900052 Role of Preoperative Transcatheter Arterial Oily Chemoembolization for Resectable Hepatocellular Carcinoma [Elektronische Daten] [Masaaki Uchida, Hitoshi Kohno, Hirofumi Kubota, Takafumi Hayashi, Akira Yamanoi, Takeo Kimoto, Takashi Ono, Naofumi Nagasue] Abstract. To clarify the effect of preoperative transcatheter arterial oily chemoembolization (TAOE) for resectable hepatocellular carcinoma (HCC) on long-term survival after curative resection, we retrospectively evaluated 60 patients with and 68 patients without preoperative TAOE. Although there was no substantial difference in the clinical backgrounds between the two groups, the 5-year survival rate was lower for the patients with preoperative TAOE than for those without TAOE: 24% versus 63%, respectively (: p < 0.05). A worse survival rate was particularly observed for the cirrhotic patients with TAOE than for those without TAOE: 35% and 72% at 4 years, respectively ( p < 0.01). As the cause of death, liver failure and gastrointestinal bleeding were more frequent in the patients with TAOE (13.3% versus 1.5%; p < 0.05). Although the TAOE seemed to retard intrahepatic recurrence during the first 1.5 years after operation (1.7% versus 10.3%; p < 0.05), the overall cancer death rate was similar between the two groups (18.3% versus 11.8%). Therefore we suggest that preoperative TAOE must not be performed for resectable HCC as a routine procedure, particularly in patients with cirrhosis. A prospective randomized trial is warranted to elucidate the merits and demerits of preoperative TAOE for surgically resectable HCC. 1996 by the Société Internationale de Chir, ugie Uchida Masaaki Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut Kohno Hitoshi Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut Kubota Hirofumi Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut Hayashi Takafumi Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut Yamanoi Akira Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut Kimoto Takeo Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut Ono Takashi Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut Nagasue Naofumi Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut https://doi.org/10.1007/s002689900052 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689900052 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Uchida Masaaki Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut NATIONALLICENCE 700 1- Kohno Hitoshi Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut NATIONALLICENCE 700 1- Kubota Hirofumi Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut NATIONALLICENCE 700 1- Hayashi Takafumi Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut NATIONALLICENCE 700 1- Yamanoi Akira Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut NATIONALLICENCE 700 1- Kimoto Takeo Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut NATIONALLICENCE 700 1- Ono Takashi Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut NATIONALLICENCE 700 1- Nagasue Naofumi Second Department of Surgery, Shimane Medical University, Izumo 693, Japan, JP aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer