caa a22 4500 477035744 CHVBK 20180405111304.0 cr unu---uuuuu 170330e19960501xx s 000 0 eng 10.1007/s002689900074 doi (NATIONALLICENCE)springer-10.1007/s002689900074 Multiple Organ Failure: Is It Disappearing? [Elektronische Daten] [Jeffrey H. Levine, Rodney M. Durham, John Moran, Arthur Baue] Abstract. The incidence of multiple organ failure (MOF) during the last decade has been reported variously as 2% to 25%, depending on the patient population examined. The mortality rate from this devastating complication ranges from 40% to 80%. Although the incidence has not changed during the last decade, it does not mean that there has been no progress. Tertiary centers are now seeing trauma and nontrauma patients who have more significant underlying disease and injuries. Likewise, a higher percentage of our trauma patients are now referred from outside institutions where there may not be the facilities to administer the complex, rapid resuscitation these patients require. Prevention of MOF remains its best treatment. Rapid, adequate volume resuscitation, adequate nutrition, appropriate antibiotic usage, and aggressive pulmonary management are important for preventing the downward physiologic spiral that leads to MOF and death. Once MOF has occurred, it is not clear that these same measures are as effective in altering outcome.: 1996 by the Société Internationale de Chir, ugie Levine Jeffrey H. Department of Surgery, St. Louis University Medical Center, 3635 Vista Boulevard, St. Louis, Missouri 63110, U.S.A., US aut Durham Rodney M. Department of Surgery, St. Louis University Medical Center, 3635 Vista Boulevard, St. Louis, Missouri 63110, U.S.A., US aut Moran John Department of Surgery, St. Louis University Medical Center, 3635 Vista Boulevard, St. Louis, Missouri 63110, U.S.A., US aut Baue Arthur Department of Surgery, St. Louis University Medical Center, 3635 Vista Boulevard, St. Louis, Missouri 63110, U.S.A., US aut https://doi.org/10.1007/s002689900074 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689900074 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Levine Jeffrey H. Department of Surgery, St. Louis University Medical Center, 3635 Vista Boulevard, St. Louis, Missouri 63110, U.S.A., US aut NATIONALLICENCE 700 1- Durham Rodney M. Department of Surgery, St. Louis University Medical Center, 3635 Vista Boulevard, St. Louis, Missouri 63110, U.S.A., US aut NATIONALLICENCE 700 1- Moran John Department of Surgery, St. Louis University Medical Center, 3635 Vista Boulevard, St. Louis, Missouri 63110, U.S.A., US aut NATIONALLICENCE 700 1- Baue Arthur Department of Surgery, St. Louis University Medical Center, 3635 Vista Boulevard, St. Louis, Missouri 63110, U.S.A., US aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer