caa a22 4500 477035779 CHVBK 20180405111304.0 cr unu---uuuuu 170330e19960501xx s 000 0 eng 10.1007/s002689900066 doi (NATIONALLICENCE)springer-10.1007/s002689900066 Goris R.J.A. Department of Surgery, University Hospital Nijmegen, 6500 HB Nijmegen, The Netherlands, NL aut MODS/SIRS: Result of an Overwhelming Inflammatory Response? [Elektronische Daten] [R.J.A. Goris] Abstract. Multiple organ dysfunction syndrome and the systemic inflammatory response syndrome are expressions of an inappropriate, generalized inflammatory response to severe inflammatory stimuli, which may be bacterial or nonbacterial in nature. The clinical signs and symptoms, morphologic alterations, and changes in oxygen transport seem to be the direct effect of phagocyte activation. So far, identifying the microorganisms and neutralizing their toxins has not been helpful in improving prognosis. As an essential adjunct to treating the bacterial or nonbacterial causes, finding safe ways of modulating the phagocyte response should be considered.: 1996 by the Société Internationale de Chir, ugie https://doi.org/10.1007/s002689900066 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689900066 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Goris R.J.A. Department of Surgery, University Hospital Nijmegen, 6500 HB Nijmegen, The Netherlands, NL aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer