caa a22 4500 477036066 CHVBK 20180405111305.0 cr unu---uuuuu 170330e19961001xx s 000 0 eng 10.1007/s002689900150 doi (NATIONALLICENCE)springer-10.1007/s002689900150 Gastric Smooth Muscle Tumors: Diagnostic Dilemmas and Factors Affecting Outcome [Elektronische Daten] [Laura Sanders, Mark Silverman, Ricardo Rossi, John Braasch, Lawrence Munson] Abstract. We reviewed the 46 gastric stromal tumors that were treated at our institution between 1958 and 1992. The most common presenting symptoms were gastrointestinal bleeding, pain, and fatigue or malaise. The tumors ranged from 4 to 150 mm, with surgery most often being a wedge excision or partial gastrectomy. Abdominal computed tomography was the most specific diagnostic test obtained preoperatively. Factors associated with decreased survival included size ≥ 8 cm (: p = 0.02), more than 0-3 mitoses per 10 HPF ( p < 0.001), positive margins or unresectability ( p = 0.008), and tumor pathologic grade II or more ( p = 0.004). These tumors have an unpredictable behavior. Surgical resection with negative margins remains the best therapy, but resection for palliation is sometimes indicated as it can be associated with prolonged survival. 1996 by the Société Internationale de Chir, ugie Sanders Laura Department of Surgery, Lahey Clinic, Burlington, Massachusetts 01803, U.S.A., US aut Silverman Mark Department of Pathology, Lahey Clinic, Burlington, Massachusetts 01803, U.S.A., US aut Rossi Ricardo Department of Surgery, Lahey Clinic, Burlington, Massachusetts 01803, U.S.A., US aut Braasch John Department of Surgery, Lahey Clinic, Burlington, Massachusetts 01803, U.S.A., US aut Munson Lawrence Department of Surgery, Lahey Clinic, Burlington, Massachusetts 01803, U.S.A., US aut https://doi.org/10.1007/s002689900150 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689900150 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sanders Laura Department of Surgery, Lahey Clinic, Burlington, Massachusetts 01803, U.S.A., US aut NATIONALLICENCE 700 1- Silverman Mark Department of Pathology, Lahey Clinic, Burlington, Massachusetts 01803, U.S.A., US aut NATIONALLICENCE 700 1- Rossi Ricardo Department of Surgery, Lahey Clinic, Burlington, Massachusetts 01803, U.S.A., US aut NATIONALLICENCE 700 1- Braasch John Department of Surgery, Lahey Clinic, Burlington, Massachusetts 01803, U.S.A., US aut NATIONALLICENCE 700 1- Munson Lawrence Department of Surgery, Lahey Clinic, Burlington, Massachusetts 01803, U.S.A., US aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer