caa a22 4500 47703618X CHVBK 20180405111305.0 cr unu---uuuuu 170330e19961001xx s 000 0 eng 10.1007/s002689900164 doi (NATIONALLICENCE)springer-10.1007/s002689900164 Influence of Associated Viral Hepatitis Status on Recurrence of Hepatocellular Carcinoma after Hepatectomy [Elektronische Daten] [Saiho Ko, Yoshiyuki Nakajima, Hiromichi Kanehiro, Tatsuya Kin, Yukio Aomatsu, Atsushi Yoshimura, Junichiro Taki, Kazuaki Yagura, Kazuo Ohashi, Hiroshige Nakano] Abstract. The purpose of this study was to investigate the relation between the recurrence of hepatocellular carcinoma (HCC) and the histologic status of underlying chronic liver disease from a viewpoint of multicentric hepatocarcinogenesis. Sixty-eight patients who underwent curative resection of HCC and have been followed for more than 2 years are reported. Based on the microscopic findings of the noncancerous part of the liver, the patients were divided into normal liver (N,: n = 2), chronic persistent hepatitis (CPH, n = 6), chronic aggressive hepatitis (CAH, n = 31), and liver cirrhosis (LC, n = 29) according to a classification by the European Association for the Study of the Liver. Background data for the groups showed no significant differences. Recurrence was observed in none of the patients in the N and CPH groups, 26 (83.9%) of the patients in the CAH group, and 12 (41.4%) of the patients in the LC group. The cumulative disease-free survival rate of the CAH group was significantly lower than that of the CPH group ( p < 0.05) and LC group ( p < 0.01). This study revealed that the histologic status of the underlying chronic liver disease influenced the recurrence rate in patients with HCC. CAH was considered to be a risk factor for recurrence after resection of HCC. 1996 by the Société Internationale de Chir, ugie Ko Saiho First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut Nakajima Yoshiyuki First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut Kanehiro Hiromichi First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut Kin Tatsuya First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut Aomatsu Yukio First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut Yoshimura Atsushi First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut Taki Junichiro First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut Yagura Kazuaki First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut Ohashi Kazuo First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut Nakano Hiroshige First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut https://doi.org/10.1007/s002689900164 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689900164 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ko Saiho First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut NATIONALLICENCE 700 1- Nakajima Yoshiyuki First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut NATIONALLICENCE 700 1- Kanehiro Hiromichi First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut NATIONALLICENCE 700 1- Kin Tatsuya First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut NATIONALLICENCE 700 1- Aomatsu Yukio First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut NATIONALLICENCE 700 1- Yoshimura Atsushi First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut NATIONALLICENCE 700 1- Taki Junichiro First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut NATIONALLICENCE 700 1- Yagura Kazuaki First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut NATIONALLICENCE 700 1- Ohashi Kazuo First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut NATIONALLICENCE 700 1- Nakano Hiroshige First Department of Surgery, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634, Japan, JP aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer