caa a22 4500 477036260 CHVBK 20200916193757.0 cr unu---uuuuu 170330e19961001xx s 000 0 eng 10.1007/s002689900166 doi (NATIONALLICENCE)springer-10.1007/s002689900166 Application of Formaldehyde for Treatment of Hemorrhagic Radiation-Induced Proctitis [Elektronische Daten] [B. Roche, R. Chautems, M.C. Marti] Abstract. Radiation-induced proctitis with hemorrhage is not a common complication of radiotherapy to the pelvis for carcinoma. In the most severe forms, massive hemorrhage may necessitate repeated transfusions and inpatient treatment. In severe cases medical treatment has not been proved effective. Surgery may lead to serious complications and is technically difficult. Six patients who showed a hemorrhagic radiation-induced proctitis have been treated as outpatients with application of formaldehyde 4%. In four cases the bleeding ceased after the first formaldehyde application; two patients continued to bleed, but another application of formaldehyde 3 weeks later definitively controlled the hemorrhage. Follow-up evaluation at 12 months showed in each case that the hemorrhage was controlled and treated. There were no complications, such as burns or late stenoses of the deep layers of the rectum. This inexpensive technique is well tolerated by the patient, gives good long-term results, and is available at every hospital. Local application of formaldehyde 4% to the rectum may be the treatment of choice for hemorrhagic radiation-induced proctitis.: 1996 by the Société Internationale de Chir, ugie Roche B. Outpatient Department, University Hospital, 1210 Geneva 14, Switzerland, CH aut Chautems R. Outpatient Department, University Hospital, 1210 Geneva 14, Switzerland, CH aut Marti M.C. Outpatient Department, University Hospital, 1210 Geneva 14, Switzerland, CH aut https://doi.org/10.1007/s002689900166 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689900166 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Roche B. Outpatient Department, University Hospital, 1210 Geneva 14, Switzerland, CH aut NATIONALLICENCE 700 1- Chautems R. Outpatient Department, University Hospital, 1210 Geneva 14, Switzerland, CH aut NATIONALLICENCE 700 1- Marti M.C. Outpatient Department, University Hospital, 1210 Geneva 14, Switzerland, CH aut