caa a22 4500 477036384 CHVBK 20180405111306.0 cr unu---uuuuu 170330e19960601xx s 000 0 eng 10.1007/PL00012250 doi (NATIONALLICENCE)springer-10.1007/PL00012250 Blood Supply and Parathyroid Hormone Secretion in Pathological Parathyroid Glands [Elektronische Daten] [Stefan Ander, Kenth Johansson, Stafan Smeds] The blood supply of pathologic parathyroid glands and the relation between parathyroid hormone secretion and parathyroid blood perfusion was studied during surgery for hyperparathyroidism. Blood flow in 39 single adenomas and 20 glands classified as primary or secondary hyperplasia were studied intraoperatively with laser Doppler flowmetry. The ipsilateral inferior thyroid artery was occluded during continuous flowmetry recording, which resulted in a 40% reduction of parathyroid blood flow in both groups. In 12 patients with single adenomas, intact parathormone (iPTH) was measured intraoperatively before and during occlusion of the ipsilateral inferior thyroid artery and after extirpation of the adenoma. During occlusion the iPTH levels were mainly unchanged despite blood flow reduction of up to 80%. After removal of the adenoma the iPTH normalized within 15 minutes. In a control group of eight single adenomas, iPTH was measured similarly without vascular occlusion, demonstrating comparable iPTH levels. This study demonstrates similar routes of vascularization for single adenomas and hyperplastic glands, as was earlier seen for normal parathyroid glands. The increased parathyroid hormone secretion from single adenomas appears to remain mainly unchanged during significant blood flow reduction. Société Internationale de Chirugie, 1996 Ander Stefan Department of Endocrinology and Metabolism, University Hospital, 581 85, Linköping, Sweden aut Johansson Kenth Department of Endocrinology and Metabolism, University Hospital, 581 85, Linköping, Sweden aut Smeds Stafan Department of Endocrinology and Metabolism, University Hospital, 581 85, Linköping, Sweden aut World Journal of Surgery Springer-Verlag 20/5(1996-06-01), 598-602 0364-2313 20:5<598 1996 20 268 https://doi.org/10.1007/PL00012250 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/PL00012250 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ander Stefan Department of Endocrinology and Metabolism, University Hospital, 581 85, Linköping, Sweden aut NATIONALLICENCE 700 1- Johansson Kenth Department of Endocrinology and Metabolism, University Hospital, 581 85, Linköping, Sweden aut NATIONALLICENCE 700 1- Smeds Stafan Department of Endocrinology and Metabolism, University Hospital, 581 85, Linköping, Sweden aut NATIONALLICENCE 773 0- World Journal of Surgery Springer-Verlag 20/5(1996-06-01), 598-602 0364-2313 20:5<598 1996 20 268 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer