caa a22 4500 477036570 CHVBK 20180405111306.0 cr unu---uuuuu 170330e19960201xx s 000 0 eng 10.1007/s002689900025 doi (NATIONALLICENCE)springer-10.1007/s002689900025 Value of Somatostatin Receptor Scintigraphy for Preoperative Localization of Carcinoids [Elektronische Daten] [O. Kisker, R.J. Weinel, J. Geks, F. Zacara, K. Joseph, M. Rothmund] Abstract. Most carcinoid primary tumors are small and do not cause symptoms until complications (e.g. intestinal obstruction) or symptoms and signs of the carcinoid syndrome occur. Therefore in most cases an assessment of the primary tumor and its metastases must be performed. To determine the value of somatostatin receptor scintigraphy (SRS) for localizing carcinoid tumors, we compared the results of SRS with those obtained with computed tomography (CT) and ultrasonography (US) in 22 patients who had not undergone surgery for removal of the primary tumor. We could not find an advantage of SRS over CT and US for detecting the primary lesions. Tumors > 2 cm in diameter were regularly detected using all methods. SRS was not superior to CT or US for the detection of liver metastases. SRS showed the liver metastases in 16 of 18 patients, whereas CT and US detected liver metastases in all patients. For localization of extrahepatic abdominal and extraabdominal metastases (lymph nodes, bone), whole-body SRS showed an advantage over CT and US. We conclude that SRS is not superior to CT or US for localization of primary carcinoid tumors or liver metastases, although it did prove successful for visualizing extrahepatic and extraabdominal tumor spread. Additionally, SRS is useful for identifying receptor-positive metastases that may be treated by somatostatin analogs. Thus SRS should be performed in patients with a known carcinoid tumor, except those with an appendiceal carcinoid measuring < 1 cm in diameter.: 1996 by the Société Internationale de Chir, ugie Kisker O. Department of General Surgery, University Hospital, Philipps-University Marburg, Baldingerstrasse, D-35033 Marburg, Germany, DE aut Weinel R.J. Department of General Surgery, University Hospital, Philipps-University Marburg, Baldingerstrasse, D-35033 Marburg, Germany, DE aut Geks J. Department of General Surgery, University Hospital, Philipps-University Marburg, Baldingerstrasse, D-35033 Marburg, Germany, DE aut Zacara F. Department of General Surgery, University Hospital, Philipps-University Marburg, Baldingerstrasse, D-35033 Marburg, Germany, DE aut Joseph K. Department of Nuclear Medicine, University Hospital, Philipps-University Marburg, Baldingerstrasse, D-35033 Marburg, Germany, DE aut Rothmund M. Department of General Surgery, University Hospital, Philipps-University Marburg, Baldingerstrasse, D-35033 Marburg, Germany, DE aut https://doi.org/10.1007/s002689900025 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689900025 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kisker O. Department of General Surgery, University Hospital, Philipps-University Marburg, Baldingerstrasse, D-35033 Marburg, Germany, DE aut NATIONALLICENCE 700 1- Weinel R.J. Department of General Surgery, University Hospital, Philipps-University Marburg, Baldingerstrasse, D-35033 Marburg, Germany, DE aut NATIONALLICENCE 700 1- Geks J. Department of General Surgery, University Hospital, Philipps-University Marburg, Baldingerstrasse, D-35033 Marburg, Germany, DE aut NATIONALLICENCE 700 1- Zacara F. Department of General Surgery, University Hospital, Philipps-University Marburg, Baldingerstrasse, D-35033 Marburg, Germany, DE aut NATIONALLICENCE 700 1- Joseph K. Department of Nuclear Medicine, University Hospital, Philipps-University Marburg, Baldingerstrasse, D-35033 Marburg, Germany, DE aut NATIONALLICENCE 700 1- Rothmund M. Department of General Surgery, University Hospital, Philipps-University Marburg, Baldingerstrasse, D-35033 Marburg, Germany, DE aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer