caa a22 4500 477036597 CHVBK 20180405111306.0 cr unu---uuuuu 170330e19960201xx s 000 0 eng 10.1007/s002689900038 doi (NATIONALLICENCE)springer-10.1007/s002689900038 Somatostatin Receptor Localization of Pancreatic Endocrine Tumors [Elektronische Daten] [V.D. Corleto, F. Scopinaro, S. Angeletti, A. Materia, N. Basso, E. Polettini, B. Annibale, O. Schillaci, G. D'Ambra, M. Marignani, G. Gualdi, C. Bordi, E.J. Passaro, G. Delle Fave] Abstract. Gastroenteropancreatic endocrine tumors are difficult to localize. At the same time the tumor is localized, though, there is an opportunity for cure or to remove tumor tissue. In this study we have prospectively examined the ability of 111In-octreotide scintigraphy, magnetic resonance imaging (MRI), and computed tomography (CT) to localize tumor lesions in 24 patients with a biochemical or histologic diagnosis of neuroendocrine tumor. In eight patients a surgical assessment of the imaging results was prospectively performed. Planar and abdominal single-photon emission tomography (SPET) images acquired 4 and 24 hours after 180 to 220 MBq of 111In-octreotide injection were evaluated and compared with conventional imaging techniques. SPET scintigraphy visualized more presumed tumor lesions (: n = 39) than conventional imaging studies (MRI, n = 25; CT, n = 13); 23 of 24 patients had positive octreotide scintigraphy, 17 of 24 had positive MRI-scans, and 12 of 24 patients had positive CT scans. It was concluded that 111 In-octreotide scintigraphy combined with conventional imaging improves the preoperative localization of presumably tumorous lesions in patients with gastroenterohepatic endocrine tumors. 1996 by the Société Internationale de Chir, ugie Corleto V.D. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut Scopinaro F. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut Angeletti S. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut Materia A. Department of Surgery, Second Medical Clinic, Policlinico I, Via del Policlinico, University of La Sapienza, 00161 Rome, Italy, IT aut Basso N. Department of Surgery, Second Medical Clinic, Policlinico I, Via del Policlinico, University of La Sapienza, 00161 Rome, Italy, IT aut Polettini E. Department of Radiology, First Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut Annibale B. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut Schillaci O. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut D'Ambra G. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut Marignani M. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut Gualdi G. Department of Radiology, First Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut Bordi C. Department of Human Pathology, University of Parma, Via Gramsci 14, 43100 Parma, Italy, IT aut Passaro E.J. Department of Surgery, VA Medical Center West Los Angeles, 11301 Wilshire Boulevard, Los Angeles, California 90073, U.S.A., US aut Delle Fave G. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut https://doi.org/10.1007/s002689900038 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s002689900038 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Corleto V.D. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut NATIONALLICENCE 700 1- Scopinaro F. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut NATIONALLICENCE 700 1- Angeletti S. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut NATIONALLICENCE 700 1- Materia A. Department of Surgery, Second Medical Clinic, Policlinico I, Via del Policlinico, University of La Sapienza, 00161 Rome, Italy, IT aut NATIONALLICENCE 700 1- Basso N. Department of Surgery, Second Medical Clinic, Policlinico I, Via del Policlinico, University of La Sapienza, 00161 Rome, Italy, IT aut NATIONALLICENCE 700 1- Polettini E. Department of Radiology, First Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut NATIONALLICENCE 700 1- Annibale B. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut NATIONALLICENCE 700 1- Schillaci O. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut NATIONALLICENCE 700 1- D'Ambra G. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut NATIONALLICENCE 700 1- Marignani M. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut NATIONALLICENCE 700 1- Gualdi G. Department of Radiology, First Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut NATIONALLICENCE 700 1- Bordi C. Department of Human Pathology, University of Parma, Via Gramsci 14, 43100 Parma, Italy, IT aut NATIONALLICENCE 700 1- Passaro E.J. Department of Surgery, VA Medical Center West Los Angeles, 11301 Wilshire Boulevard, Los Angeles, California 90073, U.S.A., US aut NATIONALLICENCE 700 1- Delle Fave G. Department of Gastroenterology, Second Medical Clinic, Policlinico Umberto I, Via del Policlinico, University La Sapienza, 00161 Rome, Italy, IT aut Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer