caa a22 4500 477037658 CHVBK 20180405111309.0 cr unu---uuuuu 170330e19960301xx s 000 0 eng 10.1007/BF00049489 doi (NATIONALLICENCE)springer-10.1007/BF00049489 A possible role for human papillomaviruses in head and neck cancer [Elektronische Daten] [Bettie Steinberg, Teresa DiLorenzo] Human papillomaviruses (HPVs) cause benign tumors in the respiratory tract. Mounting evidence suggests that they also play a role in the etiology of a subset of head and neck cancers. Carcinomas in patients with a history of recurrent respiratory papillomatosis clearly are caused by persisting HPV interacting with one or more carcinogenic agents. Verrucous carcinomas of the oral cavity, tonsillar and tongue carcinomas are strongly linked with HPVs, based on molecular epidemiologic data. Tonsillar cancers have been shown to express HPV RNA, presumed necessary to induce and maintain a carcinoma, supporting a viral etiology. This paper reviews the molecular and cellular basis for considering HPVs as causttive agents of cancer, and reviews the literature that considers the possible role of HPVs in head and neck cancer. Kluwer Academic Publishers, 1996 papillomavirus nationallicence respiratory papillomas nationallicence tumor suppressor genes nationallicence tonsillar cancer nationallicence verrucous cancer nationallicence Steinberg Bettie Department of Otolaryngology and Communicative Disorders, Long Island Jewish Medical Center, The Long Island Campus for the Albert Einstein College of Medicine, USA aut DiLorenzo Teresa Department of Otolaryngology and Communicative Disorders, Long Island Jewish Medical Center, The Long Island Campus for the Albert Einstein College of Medicine, USA aut Cancer and Metastasis Reviews Kluwer Academic Publishers; http://www.wkap.nl 15/1(1996-03-01), 91-112 0167-7659 15:1<91 1996 15 10555 https://doi.org/10.1007/BF00049489 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00049489 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Steinberg Bettie Department of Otolaryngology and Communicative Disorders, Long Island Jewish Medical Center, The Long Island Campus for the Albert Einstein College of Medicine, USA aut NATIONALLICENCE 700 1- DiLorenzo Teresa Department of Otolaryngology and Communicative Disorders, Long Island Jewish Medical Center, The Long Island Campus for the Albert Einstein College of Medicine, USA aut NATIONALLICENCE 773 0- Cancer and Metastasis Reviews Kluwer Academic Publishers; http://www.wkap.nl 15/1(1996-03-01), 91-112 0167-7659 15:1<91 1996 15 10555 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer