caa a22 4500 477038042 CHVBK 20180405111309.0 cr unu---uuuuu 170330e19960601xx s 000 0 eng 10.1007/BF00437472 doi (NATIONALLICENCE)springer-10.1007/BF00437472 Leukocyte-endothelial adhesion and angiogenesis in tumors [Elektronische Daten] [Rakesh Jain, Gerald Koenig, Marc Dellian, Dai Fukumura, Lance Munn, Robert Melder] Leukocyte-endothelial adhesion and angiogenesis, until recently considered as separate processes, have been shown to be linked by two recent findings: soluble cellular adhesion molecules (CAMs) involved in leukocyte-endothelial interactions are angiogenic and well known angiogenic molecules secreted by cancer or immune cells can modulate the endothelial CAMs. This molecular link may partially explain why the overall leukocyte-endothelial interaction is often low and heterogeneous in angiogenic tumor vessels and why activated lymphocytes adhere nonuniformly to tumor vessels when injected into the tumor's blood supply. Kluwer Academic Publishers, 1996 adhesion molecules nationallicence angiongenesis nationallicence leukocyte-endothelial interactions nationallicence selectins nationallicence integrins nationallicence Jain Rakesh Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, 02114, Boston, MA, USA aut Koenig Gerald Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, 02114, Boston, MA, USA aut Dellian Marc Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, 02114, Boston, MA, USA aut Fukumura Dai Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, 02114, Boston, MA, USA aut Munn Lance Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, 02114, Boston, MA, USA aut Melder Robert Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, 02114, Boston, MA, USA aut Cancer and Metastasis Reviews Kluwer Academic Publishers; http://www.wkap.nl 15/2(1996-06-01), 195-204 0167-7659 15:2<195 1996 15 10555 https://doi.org/10.1007/BF00437472 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00437472 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jain Rakesh Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, 02114, Boston, MA, USA aut NATIONALLICENCE 700 1- Koenig Gerald Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, 02114, Boston, MA, USA aut NATIONALLICENCE 700 1- Dellian Marc Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, 02114, Boston, MA, USA aut NATIONALLICENCE 700 1- Fukumura Dai Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, 02114, Boston, MA, USA aut NATIONALLICENCE 700 1- Munn Lance Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, 02114, Boston, MA, USA aut NATIONALLICENCE 700 1- Melder Robert Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital, 02114, Boston, MA, USA aut NATIONALLICENCE 773 0- Cancer and Metastasis Reviews Kluwer Academic Publishers; http://www.wkap.nl 15/2(1996-06-01), 195-204 0167-7659 15:2<195 1996 15 10555 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer