caa a22 4500 47703814X CHVBK 20180405111310.0 cr unu---uuuuu 170330e19960601xx s 000 0 eng 10.1007/BF00437473 doi (NATIONALLICENCE)springer-10.1007/BF00437473 Tumor angiogenesis: A physiological process or genetically determined? [Elektronische Daten] [Patricia D'Amore, David Shima] Continued tumor growth is dependent upon the growth of new blood vessels. This commentary reviews the mechanisms whereby tumors become vascularized and examines whether tumor angiogenesis is solely an example of a normal physiologic process or is part of the genetic program of the tumor. The likelihood that neovascularization of tumors combines both of these components, that is, utilizing tumor-specific elements as well as capacities common to all cells, is discussed. Kluwer Academic Publishers, 1996 hypoxia nationallicence neovascularization nationallicence vascular endothelial growth factor nationallicence tumor suppressors nationallicence oncogenes nationallicence D'Amore Patricia Laboratory for Surgical Research, Children's Hospital, 02115, Boston, MA, USA aut Shima David Cell Biology Laboratory, Imperial Cancer Research Fund, London, England aut Cancer and Metastasis Reviews Kluwer Academic Publishers; http://www.wkap.nl 15/2(1996-06-01), 205-212 0167-7659 15:2<205 1996 15 10555 https://doi.org/10.1007/BF00437473 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00437473 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- D'Amore Patricia Laboratory for Surgical Research, Children's Hospital, 02115, Boston, MA, USA aut NATIONALLICENCE 700 1- Shima David Cell Biology Laboratory, Imperial Cancer Research Fund, London, England aut NATIONALLICENCE 773 0- Cancer and Metastasis Reviews Kluwer Academic Publishers; http://www.wkap.nl 15/2(1996-06-01), 205-212 0167-7659 15:2<205 1996 15 10555 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer