caa a22 4500 477038433 CHVBK 20180405111310.0 cr unu---uuuuu 170330e19961001xx s 000 0 eng 10.1007/BF02740638 doi (NATIONALLICENCE)springer-10.1007/BF02740638 The role of swelling-induced anion channels during neuronal volume regulation [Elektronische Daten] [Srisaila Basavappa, J. Ellory] Regulation of cell volume is an essential function of most mammalian cells. In the cells of the central nervous system, maintenance of cell osmolarity and, hence, volume, is particularly crucial because of the restrictive nature of the skull. Cell volume regulation involves a variety of pathways, with considerable differences between cell types. One common pathway activated during hypo-osmotic stress involves chloride (Cl−) channels. However, hypo-osmotically stimulated anion permeability can be regulated by a diverse array of second messengers. Although neuronal swelling can occur in a number of pathological and nonpathological conditions, our understanding of neuronal volume regulation is limited. This article summarizes our current understanding of the role of anion channels during neuronal volume regulation. Humana Press Inc, 1996 Volume regulation nationallicence regulatory volume decrease (RVD) nationallicence Cl−-channels nationallicence amino acids nationallicence calcium nationallicence arachidonic acid nationallicence stretch-sensitive channels nationallicence P-glycoprotein nationallicence Basavappa Srisaila University Laboratory of Physiology, University of Oxford, Parks Rd., OX1 3PT, Oxford, UK aut Ellory J. University Laboratory of Physiology, University of Oxford, Parks Rd., OX1 3PT, Oxford, UK aut Molecular Neurobiology Humana Press 13/2(1996-10-01), 137-153 0893-7648 13:2<137 1996 13 12035 https://doi.org/10.1007/BF02740638 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02740638 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Basavappa Srisaila University Laboratory of Physiology, University of Oxford, Parks Rd., OX1 3PT, Oxford, UK aut NATIONALLICENCE 700 1- Ellory J. University Laboratory of Physiology, University of Oxford, Parks Rd., OX1 3PT, Oxford, UK aut NATIONALLICENCE 773 0- Molecular Neurobiology Humana Press 13/2(1996-10-01), 137-153 0893-7648 13:2<137 1996 13 12035 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer